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New treatment option for Aging
Official title Mode of Exercise and Bone Biomarkers in Older Veterans
ClinicalTrials.gov ID: NCT05266976
What this study is testing
- What it's testing
- Adults are often encouraged to exercise to maintain or improve bone health. However, there is evidence that exercise does not always lead to increases in bone mass, and exercise could lead to bone loss under certain conditions.
- Time commitment: about 10 weeks
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 60 and older. Healthy volunteers may be eligible.
You may be able to join if
- Healthy older (60+ y) Veteran women and men in the Denver Metro Area
- Normally active (e.g., recreational cycling or walking exercise)
You likely can't join if
- Impaired renal function, defined as an eGRF of \<60 mL/min/1.73m2
- Hepatobiliary disease, defined as liver function tests (AST, ALT) \>1.5 times the upper limit of normal
- Thyroid dysfunction, defined as an ultrasensitive thyroid stimulating hormone (TSH) \ 5.0 mU/L
- Serum Ca \ 10.3 mg/dL
- Serum 25(OH)D \<20 ng/mL
- Uncontrolled hypertension, defined as resting systolic blood pressure (BP) \>150 mmHg or diastolic BP \>90 mmHg;
See the full eligibility criteria
- Healthy older (60+ y) Veteran women and men in the Denver Metro Area
- Normally active (e.g., recreational cycling or walking exercise)
- Impaired renal function, defined as an eGRF of \<60 mL/min/1.73m2
- Hepatobiliary disease, defined as liver function tests (AST, ALT) \>1.5 times the upper limit of normal
- Thyroid dysfunction, defined as an ultrasensitive thyroid stimulating hormone (TSH) \ 5.0 mU/L
- Serum Ca \ 10.3 mg/dL
- Serum 25(OH)D \<20 ng/mL
- Uncontrolled hypertension, defined as resting systolic blood pressure (BP) \>150 mmHg or diastolic BP \>90 mmHg;
- History of type 1 or type 2 diabetes
- Cardiovascular disease, defined as subjective or objective indicators of ischemic heart disease (e.g., angina, ST segment depression) or serious arrhythmias at rest or during the graded exercise test (GXT). Volunteers...
- Anemia, defined as a serum hemoglobin \<12.1 g/dL for women and \<14.3 g/dL for men
- Fracture in the past 6 months
- Current diagnosis or symptoms of COVID-19 In the event of abnormal BP, live function, TSH, 25(OH)D, or hemoglobin values, volunteers can be reassessed, including after appropriate follow-up evaluation and treatment by a...
The study team makes the final eligibility decision.
Where it's taking place
- Aurora, Colorado, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 10 weeks per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 60 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Aurora, Colorado, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.