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New treatment option for Non-hodgkin Lymphoma
Official title Chemoradiotherapy With Targeted Immunotherapy in Pediatric Lymphoma
ClinicalTrials.gov ID: NCT05253495
What this study is testing
What is DOC Group B?
DOC Group B is an investigational medicine, being studied as a potential treatment for non-hodgkin lymphoma.
Also referred to as Reduction Phase.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The addition of targeted immunotherapy will be safe and well tolerated and facilitate the reduction of anthracycline exposure while preserving lymphoma disease control in children, adolescents and young adults (CAYA) with mature B-cell non-Hodgkin lymphoma (MB-NHL) and classical Hodgkin lymphoma (cHL).
- Phase 2: a mid-size study of how well it works
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 3 to 39
You may be able to join if
- Newly diagnosed patients with histologically or cytologically proven newly diagnosed MB-NHL or cHL according to WHO Classification who meet the...
- Adequate organ function
You likely can't join if
- Primary mediastinal B-cell lymphoma (PMBL)
- T-cell/histiocyte-rich large B-cell lymphoma
- Gray zone lymphoma
- Follicular lymphoma
- Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL)
- Posttransplant lymphoproliferative lymphoma (PTLD)
The study team makes the final eligibility decision.
Where it's taking place
- Birmingham, Alabama, United States
- Gainsville, Florida, United States
- Vallhala, New York, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 3 years to 39 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Birmingham, Alabama, United States; Gainsville, Florida, United States; Vallhala, New York, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.