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New treatment option for Zinc Deficiency
Official title Effects of Daily Beef Intake, as a Component of a Heart-Healthy Diet on Cellular Zinc
ClinicalTrials.gov ID: NCT05236374
What this study is testing
- What it's testing
- The objective of the current study is to test the overarching hypothesis that the beef nutritive matrix is uniquely suited to direct dietary zinc to cellular compartments for improved metabolic function, leading to a greater effect on health outcomes. Specifically, whether beef, as a component of a healthy meal, will promote the absorption of zinc into cells, where the zinc will have greater effects on zinc-dependent metabolic processes supporting cardiovascular health.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 55 to 70. Healthy volunteers may be eligible.
You may be able to join if
- Male or postmenopausal female 55-70 years of age
- Women: lack of menses for at least two years.
- Subject is willing and able to comply with the study protocols.
- Subject is willing to participate in all study procedures
- Self-reported stable dose of prescribed medications for a minimum of 6 months
You likely can't join if
- Self-reported use of daily anticoagulation agents including aspirin, NSAIDs
- Prescribed metaformin, statins or medications known to interfere with zinc, protein, or lipid metabolism
- Vegan, Vegetarians, food faddists or those consuming a non-traditional diet (e.g. Adkins, Keto, Paleo, etc.)
- Fruit consumption ≥ 3 cups/day
- Regular consumption of strawberries (2-3 servings/week)
- Vegetable consumption ≥ 4 cups/day
See the full eligibility criteria
- Male or postmenopausal female 55-70 years of age
- Women: lack of menses for at least two years.
- Subject is willing and able to comply with the study protocols.
- Subject is willing to participate in all study procedures
- Self-reported stable dose of prescribed medications for a minimum of 6 months
- BMI 18.5 - 29.9 kg/m2
- Self-reported use of daily anticoagulation agents including aspirin, NSAIDs
- Prescribed metaformin, statins or medications known to interfere with zinc, protein, or lipid metabolism
- Vegan, Vegetarians, food faddists or those consuming a non-traditional diet (e.g. Adkins, Keto, Paleo, etc.)
- Fruit consumption ≥ 3 cups/day
- Regular consumption of strawberries (2-3 servings/week)
- Vegetable consumption ≥ 4 cups/day
- Coffee/tea ≥ 3 cups/day
- Dark chocolate ≥ 3 oz/day
- Alcohol intake greater than 2 drinks in a day for men, or 1 drink in a day for women.
- Self-reported restriction of physical activity due to a chronic health condition
- Self-reported chronic/routine high intensity exercise
- Self-reported diabetes
- Blood pressure ≥ 140/90 mm Hg
- Self-reported renal or liver disease
- Self-reported heart disease, which includes cardiovascular events and stroke
- Peripheral artery disease Raynaud's syndrome or disease
- Inability to properly place or wear the PAT probes or abnormal measurements on pre-screening PAT
- Self-reported cancer within past 5 years
- Self-reported malabsorption
- Unwillingness to stop any supplement use six weeks prior to study initiation, including multivitamin/mineral, powders, herbal, plant or botanical, pro- and prebiotics, and oil supplements.
- Smoking, vaping, cannabis use
- Current enrollee in a clinical research study.
The study team makes the final eligibility decision.
Where it's taking place
- Davis, California, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 55 years to 70 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Davis, California, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.