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New treatment option for Critically Ill
Official title The Effects of Pancreatic Enzyme Supplementation in Critically Ill Patients on Enteral Feeding
ClinicalTrials.gov ID: NCT05112328
What this study is testing
What is Exocrine Pancreatic Enzyme?
Exocrine Pancreatic Enzyme is an investigational medicine, being studied as a potential treatment for critically ill.
Also referred to as Norzyme.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Determine the effect of high-dose pancreatic enzyme supplementation on nutritional indicators and clinical course in critically ill patients undergoing enteral nutrition.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Adults 19 years and older
- Hospitalized in the surgical/medical intensive care unit of the Seoul National University Hospital
- Enteral nutrition
- Patients who consented to this study
- Patients with risk factors for pancreatic exocrine dysfunction
You likely can't join if
- chronic pancreatitis
- unresectable pancreatic cancer
- History of pancreatectomy
- Underlying diseases in which the effect of Exocrine pancreatic enzyme administration is difficult to show
- Inflammatory bowel disease
- Short bowel syndrome
See the full eligibility criteria
- Adults 19 years and older
- Hospitalized in the surgical/medical intensive care unit of the Seoul National University Hospital
- Enteral nutrition
- Patients who consented to this study
- Patients with risk factors for pancreatic exocrine dysfunction
- Shock (Norepinephrine)
- Sepsis (3 rd definition of sepsis)
- Diabetes
- Cardiac arrest
- hyperlactatemia serum lactate \> 2 mmol/L)
- Mechanical ventilation
- Continuous renal replacement therapy
- chronic pancreatitis
- unresectable pancreatic cancer
- History of pancreatectomy
- Underlying diseases in which the effect of Exocrine pancreatic enzyme administration is difficult to show
- Inflammatory bowel disease
- Short bowel syndrome
The study team makes the final eligibility decision.
Where it's taking place
- Seoul, Jongno-gu, South Korea
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Seoul, Jongno-gu, South Korea. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.