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New treatment option for Laryngeal Dystonia
Official title Effects of Neuromodulation in Laryngeal Dystonia
ClinicalTrials.gov ID: NCT05095740
What this study is testing
- What it's testing
- Laryngeal dystonia (LD) causes excessive vocal fold abduction (opening) or adduction (closing) leading to decreased voice quality, job prospects, self-worth and quality of life. Individuals with LD often experience episodic breathy voice, decreased ability to sustain vocal fold vibration, frequent pitch breaks and in some cases, vocal tremor.
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 21 to 85. Healthy volunteers may be eligible.
You may be able to join if
- Age range is 21-85 years
- Diagnosis of Laryngeal Dystonia (LD)
- Subject is able to give informed consent
- Symptoms at worst severity if receiving botulinum toxin injections
- Subject has signed the consent form
You likely can't join if
- Other forms of dystonia
- Vocal fold pathology or paralysis
- Essential tremor
- Laryngeal cancer or other neurologic conditions with medications affecting the central nervous system
- History of laryngeal surgery
- Adults lacking the ability to consent or complete the assessments and intervention
See the full eligibility criteria
- Age range is 21-85 years
- Diagnosis of Laryngeal Dystonia (LD)
- Subject is able to give informed consent
- Symptoms at worst severity if receiving botulinum toxin injections
- Subject has signed the consent form
- Other forms of dystonia
- Vocal fold pathology or paralysis
- Essential tremor
- Laryngeal cancer or other neurologic conditions with medications affecting the central nervous system
- History of laryngeal surgery
- Adults lacking the ability to consent or complete the assessments and intervention
- Seizure in the last 2 years
- Contraindications to rTMS
The study team makes the final eligibility decision.
Where it's taking place
- Boston, Massachusetts, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 21 years to 85 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Boston, Massachusetts, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.