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New treatment option for Vascular Cognitive Impairment
Official title Exercise as a Primer for Brain Stimulation in Vascular Cognitive Impairment No Dementia (VCIND)
ClinicalTrials.gov ID: NCT05079464
What this study is testing
- What it's testing
- People with vascular conditions are at risk of having memory problems, and these memory problems increase the risk for further cognitive decline. Brain stimulation has been used to improve mood and memory.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 50 and older
You may be able to join if
- ≥50 years of age; females must be post-menopausal
- Presence of cerebrovascular and/or cardiovascular risk factors or coronary artery disease
- Montreal Cognitive Assessment (MoCA) \<27
- Sufficiently proficient in English
- Must be able to exercise at a moderate intensity level
You likely can't join if
- History of stroke
- Change in psychotropics within the last 4 weeks
- Current benzodiazepine use due
- Metal implants that would preclude safe use of tDCS or neuroimaging
- Significant neurological or psychiatric conditions (current major depressive disorder, bipolar disorder, schizophrenia)
- MoCA \<18 and/or clinical diagnosis of dementia
See the full eligibility criteria
- ≥50 years of age; females must be post-menopausal
- Presence of cerebrovascular and/or cardiovascular risk factors or coronary artery disease
- Montreal Cognitive Assessment (MoCA) \<27
- Sufficiently proficient in English
- Must be able to exercise at a moderate intensity level
- Presence of modest deficits (1 standard deviation below population norm) in one of the following domains: executive function, verbal memory, working memory, or visuospatial memory
- History of stroke
- Change in psychotropics within the last 4 weeks
- Current benzodiazepine use due
- Metal implants that would preclude safe use of tDCS or neuroimaging
- Significant neurological or psychiatric conditions (current major depressive disorder, bipolar disorder, schizophrenia)
- MoCA \<18 and/or clinical diagnosis of dementia
- Any medical contraindications to exercise
The study team makes the final eligibility decision.
Where it's taking place
- Toronto, Ontario, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 50 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Toronto, Ontario, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.