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New treatment option for Alcohol Use Disorder
Official title Tdcs And cogNitive traininG cOmbined for AUD (TANGO)
ClinicalTrials.gov ID: NCT05062369
What this study is testing
- What it's testing
- The overarching goal of this project is to expand the traditional expertise in non-invasive neuromodulation at the University of Minnesota towards developing novel paired-neuromodulation approaches using transcranial direct current stimulation (tDCS) for new treatments for alcohol use disorder (AUD) that support long-term abstinence. This study will allow the investigators to discern whether the pairing of dorsolateral prefrontal cortex (DLPFC) stimulation and cognitive training can lead to improved treatment outcomes as it pertains to executive functioning and maintenance of abstinence.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- Meet the Diagnostic and Statistical Manual of Mental Disorders diagnostic criteria for AUD
- Abstinent from alcohol use
- Must have the intention to remain in the Lodging Plus program until the end of the intervention portion of the study.
You likely can't join if
- Any medical condition or treatment with neurological sequelae (i.e. stroke, tumor, loss of consciousness\>30 min, HIV)
- A head injury resulting in a skull fracture or a loss of consciousness exceeding 30 minutes (i.e., moderate or severe TBI)
- Any contraindications for tDCS or MRI scanning (tDCS contraindication: history of seizures; MRI contraindications; metal implants, pacemakers or any...
- Any primary psychotic disorder (e.g. schizophrenia, schizoaffective disorder); Participants with other treated and stable psychiatric disorders will...
- Presence of a condition that would render study measures difficult or impossible to administer or interpret
- Primary current substance use disorder diagnosis on a substance other than alcohol except for caffeine or nicotine
See the full eligibility criteria
- Meet the Diagnostic and Statistical Manual of Mental Disorders diagnostic criteria for AUD
- Abstinent from alcohol use
- Must have the intention to remain in the Lodging Plus program until the end of the intervention portion of the study.
- Any medical condition or treatment with neurological sequelae (i.e. stroke, tumor, loss of consciousness\>30 min, HIV)
- A head injury resulting in a skull fracture or a loss of consciousness exceeding 30 minutes (i.e., moderate or severe TBI)
- Any contraindications for tDCS or MRI scanning (tDCS contraindication: history of seizures; MRI contraindications; metal implants, pacemakers or any other implanted electrical device, injury with metal, braces, dental...
- Any primary psychotic disorder (e.g. schizophrenia, schizoaffective disorder); Participants with other treated and stable psychiatric disorders will be included
- Presence of a condition that would render study measures difficult or impossible to administer or interpret
- Primary current substance use disorder diagnosis on a substance other than alcohol except for caffeine or nicotine
- Clinical evidence for Wernicke-Korsakoff syndrome
- Left-handedness
- Entrance to the treatment program under a court mandate
The study team makes the final eligibility decision.
Where it's taking place
- Minneapolis, Minnesota, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Minneapolis, Minnesota, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.