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New treatment option for Locally Advanced Lung Non-Small Cell Carcinoma
Official title Cardiovascular Injury and Cardiac Fitness in Locally Advanced Non-Small Cell Lung Cancer Patients Receiving Model Based Personalized Chemoradiation
ClinicalTrials.gov ID: NCT05010109
What this study is testing
- What it's testing
- This study assesses cardiovascular injury and cardiac fitness in patients with non-small cell lung cancer that has spread to nearby tissue or lymph nodes (locally advanced) receiving model based personalized chemoradiation. The goal of this study is to learn more about the risk of developing heart disease as a result of chemoradiation treatment for lung cancer.
- Time commitment: about 10 years
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Patient with histologic diagnosis of non-small cell lung cancer, small cell lung cancer, or limited stage - small cell lung cancer (L-SCLC)
- The recommended treatment is thoracic radiation therapy combined with concurrent systemic therapy (chemotherapy and/or immunotherapy) with or without...
- \>/= 18 years of age
- KPS \>/= 70
- Willing and able to sign informed consents
You likely can't join if
- Unable or unwilling to give written informed consent
- Previous history of RT to the thorax overlapping with the current treatment field.
- Pregnant or breast-feeding
- Renal failure necessitating dialysis
- Unwilling to perform protocol tests
- Contraindication for any protocol tests
See the full eligibility criteria
- Patient with histologic diagnosis of non-small cell lung cancer, small cell lung cancer, or limited stage - small cell lung cancer (L-SCLC)
- The recommended treatment is thoracic radiation therapy combined with concurrent systemic therapy (chemotherapy and/or immunotherapy) with or without neoadjuvant and/or adjuvant systemic therapy (chemotherapy...
- \>/= 18 years of age
- KPS \>/= 70
- Willing and able to sign informed consents
- Willing to perform 6minute walking test
- Willing to preform required cardiac biomarker test for primary end point assessment.
- Unable or unwilling to give written informed consent
- Previous history of RT to the thorax overlapping with the current treatment field.
- Pregnant or breast-feeding
- Renal failure necessitating dialysis
- Unwilling to perform protocol tests
- Contraindication for any protocol tests
The study team makes the final eligibility decision.
Where it's taking place
- Houston, Texas, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 10 years per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Houston, Texas, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.