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New treatment option for Pancreatic Ductal Adenocarcinoma (PDAC)
Official title EUS-RFA PANCARDINAL-1 Trial
ClinicalTrials.gov ID: NCT04990609
What this study is testing
What is Neoadjuvant Chemotherapy (NAC)?
Neoadjuvant Chemotherapy (NAC) is an investigational medicine, being studied as a potential treatment for pancreatic ductal adenocarcinoma (pdac).
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The objectives of this study are to determine the feasibility, tolerability, and treatment effect of endoscopic ultrasound (EUS) radiofrequency ablation (RFA) plus standard-of-care neoadjuvant chemotherapy (NAC) in the treatment of pancreatic ductal adenocarcinoma (PDAC). Endoscopic ultrasound (EUS) radiofrequency ablation (RFA) and neoadjuvant chemotherapy (NAC) will be performed before tumor resection surgery, with the goal of shrinking a tumor or stopping the spread of cancer so that surgery might be less invasive and more effective.
- Phase 2: a mid-size study of how well it works
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Diagnosed and histologically-confirmed PDAC by biopsy
- Permanent street address
- Consent to study participation
- Axial CT scan consistent with PDAC
- No prior chemotherapy or less than 2 months of pre-operative chemotherapy for PDAC
You likely can't join if
- Male or female patients \< 18 years of age
- No permanent street address or telephone number
- Pregnant patients
- Inmates or prisoners
- Unable to provide informed consent
See the full eligibility criteria
- Diagnosed and histologically-confirmed PDAC by biopsy
- Permanent street address
- Consent to study participation
- Axial CT scan consistent with PDAC
- No prior chemotherapy or less than 2 months of pre-operative chemotherapy for PDAC
- Eastern Cooperative Oncology Group (ECOG) performance status of 0-2
- Male or female patients \< 18 years of age
- No permanent street address or telephone number
- Pregnant patients
- Inmates or prisoners
- Unable to provide informed consent
The study team makes the final eligibility decision.
Where it's taking place
- Houston, Texas, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Houston, Texas, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.