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New treatment option for Diabete Type 2
Official title Translational Study Using Human Abdominal Adipose Tissue Biopsies to Investigate the Role of Cannabinoid Receptor 1 (CB1) in Controlling Endocannabinoid and Adipokine Secretion
ClinicalTrials.gov ID: NCT04940962
What this study is testing
- What it's testing
- Abdominal obesity and type 2 diabetes are associated with the hyperactivation of the endocannabinoid system. Several animal and human studies indicate that circulating endocannabinoid (EC) levels are correlated with body fat.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80, men only. Healthy volunteers may be eligible.
You may be able to join if
- Controls:
- men or post-menopausal women aged between 18 and 80
- gave oral consent
- to undergo visceral surgery Non-diabetic obese people:
- men or post-menopausal women aged between 18 and 80
You likely can't join if
- Controls:
- Person not covered by national health insurance.
- BMI \> 30
- diabetes
- chronic inflammatory disease
- cancer undergoing chemotherapy or chemotherapy less than a year old
See the full eligibility criteria
- Controls:
- men or post-menopausal women aged between 18 and 80
- gave oral consent
- to undergo visceral surgery Non-diabetic obese people:
- men or post-menopausal women aged between 18 and 80
- BMI \> 30
- gave oral consent
- to undergo visceral surgery Obese diabetic people:
- men or post-menopausal women aged between 18 and 80
- type 2 diabetic not treated with Insulin or GLP-1 agonist
- BMI \> 30
- gave oral consent
- to undergo visceral surgery
- Controls:
- Person not covered by national health insurance.
- BMI \> 30
- diabetes
- chronic inflammatory disease
- cancer undergoing chemotherapy or chemotherapy less than a year old
- digestive cancer with recent weight loss (≥10%) and/or malnutrition
- known metastatic cancer
- cancer undergoing long-term hormonal treatment
- protected adult Non-diabetic obese people:
- Person not covered by national health insurance
- diabetes
- chronic inflammatory disease
- cancer undergoing chemotherapy or chemotherapy less than a year old
- digestive cancer with recent weight loss (≥10%) and/or malnutrition
- known metastatic cancer
- cancer undergoing long-term hormonal treatment
- protected adult Obese diabetic people:
- Person not covered by national health insurance
- chronic inflammatory disease
- cancer undergoing chemotherapy or chemotherapy less than a year old
- digestive cancer with recent weight loss (≥10%) and/or malnutrition
- known metastatic cancer
- cancer undergoing long-term hormonal treatment
- type 1 diabetes
- secondary diabetes
- protected adult
The study team makes the final eligibility decision.
Where it's taking place
- Dijon, France
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling male, 18 years to 80 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Dijon, France. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.