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Compares treatment options for Hypotension Drug-Induced
Official title Premedication With Atenolol Versus Metoprolol for Controlled Hypotensive Anesthesia During Nasal Surgeries
ClinicalTrials.gov ID: NCT04914234
What this study is testing
What is Atenolol Succinate Oral Tablet?
Atenolol Succinate Oral Tablet is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for hypotension drug-induced.
Also referred to as Tenormin tablets.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Objectives: To compare the safety and efficacy of oral atenolol versus oral metoprolol as a premedication for controlled hypotensive anesthesia during nasal surgeries. Background: Mucosal bleeding is the most frequent complication with nasal surgeries, as it interferes with the optimal visualization of the intranasal anatomy, increases operation time, and consequently increases blood loss.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 21 to 50
You may be able to join if
- American Society of Anesthesiologists (ASA) physical status ≤ II
- Age from 21 to 50 years
You likely can't join if
- ASA physical status \> II
- Age \ 50 years
- Pregnant women
- Breastfeeding
- Bronchial asthma
- Chronic obstructive pulmonary disease
See the full eligibility criteria
- American Society of Anesthesiologists (ASA) physical status ≤ II
- Age from 21 to 50 years
- ASA physical status \> II
- Age \ 50 years
- Pregnant women
- Breastfeeding
- Bronchial asthma
- Chronic obstructive pulmonary disease
- Diabetes Mellitus
- Hypertension
- Ischemic heart disease
- Rheumatic heart disease
- Heart failure
- Heart block
- Sick sinus syndrome
- Sinus bradycardia
- Chronic hypotension
- Anemia (Hb \< 10 g/dl)
- Renal or hepatic dysfunction
- Central nervous system disease
- Allergic fungal sinusitis
- Patients on beta-blockers
- Alcohol or drug abuse
- Anticoagulation therapy,
- Bleeding diathesis
- Agents influencing autonomic nervous system
- Allergy to the study drugs
- Any contraindication of oral intake
The study team makes the final eligibility decision.
Where it's taking place
- Damanhūr, El-Beheira, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 21 years to 50 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Damanhūr, El-Beheira, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.