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New treatment option for Postural Orthostatic Tachycardia Syndrome
Official title Compression Garments in the Community With POTS
ClinicalTrials.gov ID: NCT04881318
What this study is testing
What is Medications that modulate heart rate and blood pressure?
Medications that modulate heart rate and blood pressure is an investigational medicine, given as an once-daily, being studied as a potential treatment for postural orthostatic tachycardia syndrome.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Compression Garments are a commonly prescribed treatment in Postural Orthostatic Tachycardia Syndrome (POTS). The effectiveness of a proof-of-concept compression garment has been demonstrated in an acute laboratory setting.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 60
You may be able to join if
- Physician diagnosis of Postural Tachycardia Syndrome (POTS)
- Resident of Canada
- Owns waist-high compression garment: medical grade or commercially available tights with a pressure rating provided (e.g. 15-18 mmHg, 20-30 mmHg...
- Optional Sub-Study: owns an abdominal compression garment (e.g. abdominal shapewear, waist high shorts)
- Able to participate in a 4-day study (2x2 day segments with a 5-day washout period)
You likely can't join if
- Overt cause for postural tachycardia (i.e., acute dehydration, thyroid disease) that precludes POTS diagnosis
- Not a resident of Canada
- Participants with somatization or severe anxiety symptoms will be excluded
- Pregnant (self-reported)
- Inability to tolerate compression garments for the duration of the study
- Does not own a waist-high compression garment
See the full eligibility criteria
- Physician diagnosis of Postural Tachycardia Syndrome (POTS)
- Resident of Canada
- Owns waist-high compression garment: medical grade or commercially available tights with a pressure rating provided (e.g. 15-18 mmHg, 20-30 mmHg, 30-40 mmHg)
- Optional Sub-Study: owns an abdominal compression garment (e.g. abdominal shapewear, waist high shorts)
- Able to participate in a 4-day study (2x2 day segments with a 5-day washout period)
- Overt cause for postural tachycardia (i.e., acute dehydration, thyroid disease) that precludes POTS diagnosis
- Not a resident of Canada
- Participants with somatization or severe anxiety symptoms will be excluded
- Pregnant (self-reported)
- Inability to tolerate compression garments for the duration of the study
- Does not own a waist-high compression garment
- Other factors which in the investigator's opinion would prevent the participant from completing the protocol, including poor compliance during previous studies
The study team makes the final eligibility decision.
Where it's taking place
- Calgary, Alberta, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 60 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Calgary, Alberta, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.