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New treatment option for Chronic Rhinosinusitis With Nasal Polyps
Official title Olfactory Outcomes of Dupilumab Treatment for Nasal Polyposis
ClinicalTrials.gov ID: NCT04869436
What this study is testing
What is Dupilumab 300 MG/2 ML Subcutaneous Solution [DUPIXENT]?
Dupilumab 300 MG/2 ML Subcutaneous Solution [DUPIXENT] is an investigational medicine, given as an injection under the skin, being studied as a potential treatment for chronic rhinosinusitis with nasal polyps.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study aims to investigate the olfactory TDI score (Threshold, Discrimination, Identification) using the Sniffin' sticks test for patients with chronic rhinosinusitis with nasal polyps (CRSwNP) on dupilumab. Twenty-seven adult patients will be followed up during the treatment with dupilumab on three visits to the Otolaryngology Clinic (Baseline, 3 months and 6 months).
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Patients older than 18 years old
- Chronic rhinosinusitis with Nasal Polyps
- Olfactory loss
- Clinical indication for treatment with Dupilumab
You likely can't join if
- Patients with olfactory loss from other causes such as:
- Sinonasal malignancies
- Trauma
- Idiopathic olfactory loss
- Use of cocaine
- COVID-19 related olfactory loss
See the full eligibility criteria
- Patients older than 18 years old
- Chronic rhinosinusitis with Nasal Polyps
- Olfactory loss
- Clinical indication for treatment with Dupilumab
- Patients with olfactory loss from other causes such as:
- Sinonasal malignancies
- Trauma
- Idiopathic olfactory loss
- Use of cocaine
- COVID-19 related olfactory loss
- Pregnancy
The study team makes the final eligibility decision.
Where it's taking place
- London, Ontario, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include London, Ontario, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.