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New treatment option for Borderline Personality Disorder
Official title NEUROIMAGING OF ADOLESCENT BORDERLINE PERSONALITY DISORDER WITH AND WITHOUT POST-TRAUMATIC STRESS DISORDER
ClinicalTrials.gov ID: NCT04852744
What this study is testing
- What it's testing
- Borderline personality disorder (BPD) is a common mental disorder in adolescents with significant individual and societal repercussions, characterized over the long term by emotional hyperresponsiveness, relational instability, identity disturbances and self-aggressive behavior. The etiology of BPD is multifactorial and involves exposure to traumatic life events, which are present in the majority of cases.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 13 to 18, women only. Healthy volunteers may be eligible.
You may be able to join if
- For the 3 groups:
- female
- Age between 13 and 17 years inclusive
- Oral and written comprehension of the French language
- Affiliation to the social security scheme
You likely can't join if
- \- Illiteracy / illiteracy
- Sensory disorder (visual, auditory)
- Severe chronic psychiatric comorbidity: autism spectrum disorder, intellectual disability, schizophrenia spectrum disorder and other psychotic...
- Severe or current brain pathology (chronic neurological disease, encephalitis, history of severe head trauma), alertness disorder
- History of anoxic coma
- Contraindication to MRI (magnetic foreign body, claustrophobia, contraindication to prolonged lying down)
See the full eligibility criteria
- For the 3 groups:
- female
- Age between 13 and 17 years inclusive
- Oral and written comprehension of the French language
- Affiliation to the social security scheme
- Informed consent signed by the legal representatives holding the exercise of parental authority and the adolescent herself For patients:
- Diagnosis of borderline personality disorder according to the criteria of the Diagnostic and Statistical Manual for mental disorders, fifth edition (DSM-5; American Psychiatric Association, 2013; SIDP-IV)
- Level of general psychopathology compatible with participation in the study (score\> 20 on the CGA-S) TB + / PTSD + group: \- Post-traumatic stress disorder according to DSM-5 criteria (American Psychiatric Association...
- Absence of mental disorder according to DSM-5 criteria (American Psychiatric Association, 2013; K-SADS-PL and SIDP-IV)
- Oral and written comprehension of the French language
- Informed consent signed by the legal representative, the holder (s) of the exercise of parental authority and the adolescent herself
- \- Illiteracy / illiteracy
- Sensory disorder (visual, auditory)
- Severe chronic psychiatric comorbidity: autism spectrum disorder, intellectual disability, schizophrenia spectrum disorder and other psychotic disorders, bipolar disorder
- Severe or current brain pathology (chronic neurological disease, encephalitis, history of severe head trauma), alertness disorder
- History of anoxic coma
- Contraindication to MRI (magnetic foreign body, claustrophobia, contraindication to prolonged lying down)
- Severe physical pathology in progress
- Moving outside the Normandy region planned within 18 months
- The inclusion of the subject in another biomedical research protocol (during the present study)
- Intellectual deficit (IQ \<70)
- Pregnant or breastfeeding women
The study team makes the final eligibility decision.
Where it's taking place
- Caen, France
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 13 years to 18 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Caen, France. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.