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New treatment option for Acute Aortic Syndrome
Official title Protective Effect of Statin Against Negative Cardiovascular Remodeling and Organ Dysfunction After Acute Aortic Syndrome Surgery (PANDA III)
ClinicalTrials.gov ID: NCT04699279
What this study is testing
What is Rosuvastatin 10mg?
Rosuvastatin 10mg is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for acute aortic syndrome.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Acute Aortic Syndrome (AAS)/Aortic Aneurysm is a common feature of aortic wall events, including aortic dissection, intramural hematoma, aortic ulceration and aortic trauma, and occurs in up to 35 cases per 100,000 cases per year between the ages of 65 and 75 years. Increased levels of the inflammatory biomarker high-sensitivity C-reactive protein predict cardiovascular events.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 85
You may be able to join if
- (1) Patients with aortic dissection/ulceration/intermural hematoma/aortic aneurysm who underwent aortic arch replacement or endoluminal isolation or...
- (2) Paitents without clinically significant hyperlipidemia but with cardiovascular disease risk factors (such as male ≥45 years old, female ≥55 years...
- (3) Patients are between 18 and 85 years old, male or female;
- (4) Agree to participate in the study and sign the informed consent.
You likely can't join if
- (1) Patients with allergy to statins;
- (2) patients with active liver disease;
- (3) patients with myopathy;
- (4) Lactating women and pregnant women;
- (5) Patients with mental diseases, drug and alcohol dependence;
- (6) Refuse to participate in the study or sign the informed consent.
The study team makes the final eligibility decision.
Where it's taking place
- Guangzhou, Guangdong, China
- Nanjing, Jiangsu, China
- Qingdao, Shandong, China
- Chengdu, Sichuan, China
- Beijing, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 85 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Guangzhou, Guangdong, China; Nanjing, Jiangsu, China; Qingdao, Shandong, China; Chengdu, Sichuan, China; Beijing, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.