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New treatment option for Rumination
Official title Mechanisms and Predictors of Change in App-Based Mindfulness Training for Adolescents
ClinicalTrials.gov ID: NCT04697966
What this study is testing
- What it's testing
- A growing body of research implicates rumination as being a transdiagnostic risk factor involved in the development of depression and anxiety in youth. Critically, mindfulness meditation has shown significant promise in targeting rumination, and ultimately improving depressive and anxiety symptoms.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 13 to 18. Healthy volunteers may be eligible.
You may be able to join if
- Both genders, all ethnicities (see Section: Inclusion of Women and Minorities)
- Ages 13-18 years
- Written informed assent/consent from adolescent and parent/guardian
- English as a first language or English fluency
- Right-handed
You likely can't join if
- History or current diagnosis of any of the following DSM-5 disorders: schizophrenia spectrum or other psychotic disorder, bipolar disorder...
- Systemic medical or neurological illness that could impact fMRI measures of cerebral blood flow
- Failure to meet standard exclusion criteria for fMRI scanning (e.g. pregnancy, claustrophobia, cardiac or neural pacemakers, surgically implanted...
- History of seizure disorder, or head trauma with loss of consciousness \> 2 mins
- Serious or unstable medical illness (e.g., cardiovascular, hepatic, renal, respiratory, endocrine, neurologic or hematologic disease)
- Participants with active suicidal ideation will be immediately referred to appropriate clinical treatment.
See the full eligibility criteria
- Both genders, all ethnicities (see Section: Inclusion of Women and Minorities)
- Ages 13-18 years
- Written informed assent/consent from adolescent and parent/guardian
- English as a first language or English fluency
- Right-handed
- Personal iPhone or Android smartphone
- CRSQ rumination subscale score
- If on psychotropic medication, must be on stable dose for at least 2 months
- History or current diagnosis of any of the following DSM-5 disorders: schizophrenia spectrum or other psychotic disorder, bipolar disorder, substance/alcohol use disorder within the past 12 months or lifetime severe...
- Systemic medical or neurological illness that could impact fMRI measures of cerebral blood flow
- Failure to meet standard exclusion criteria for fMRI scanning (e.g. pregnancy, claustrophobia, cardiac or neural pacemakers, surgically implanted metal devices, cochlear implants, metal objects in the body)
- History of seizure disorder, or head trauma with loss of consciousness \> 2 mins
- Serious or unstable medical illness (e.g., cardiovascular, hepatic, renal, respiratory, endocrine, neurologic or hematologic disease)
- Participants with active suicidal ideation will be immediately referred to appropriate clinical treatment.
- Current or past treatment with mindfulness-based psychotherapy (e.g., MBCT, DBT or ACT)
- Exposure to in-person or app-based mindfulness/meditation course (at least 300 mins of past practice)
The study team makes the final eligibility decision.
Where it's taking place
- Belmont, Massachusetts, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 13 years to 18 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Belmont, Massachusetts, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.