BridgeMD
New treatment option for Weaning Failure
Official title Improving Our Understanding of Respiratory Muscle Training to Facilitate Weaning From Mechanical Ventilation in the ICU
ClinicalTrials.gov ID: NCT04658498
What this study is testing
- What it's testing
- Mechanical ventilation is a life-saving treatment frequently applied in intensive care unit (ICU). Nonetheless, by putting at rest the respiratory muscles, it can lead to respiratory muscle weakness and atrophy, which are accompanied by prolonged duration of mechanical ventilation, difficult weaning and increased ICU mortality.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Difficult and prolonged weaning patients
- Adequate oxygenation
- Febrile temperature \< 38ºC
- Hemodynamic stability
- Stable blood pressure
You likely can't join if
- Pre-existing neuromuscular disease
- Agitation
- Hemodynamically instable (arrhythmia, decompensated heart failure, coronary insufficiency)
- Hemoptysis
- Diaphoresis
- Spinal cord injury above T8
See the full eligibility criteria
- Difficult and prolonged weaning patients
- Adequate oxygenation
- Febrile temperature \< 38ºC
- Hemodynamic stability
- Stable blood pressure
- No or minimal vasopressors
- No myocardial ischemia
- Adequate hemoglobin and mentation
- Resolution of disease acute phase
- Able to follow simple verbal commands related to IMT
- Mechanically ventilated via a tracheostomy or endotracheal tube
- Pre-existing neuromuscular disease
- Agitation
- Hemodynamically instable (arrhythmia, decompensated heart failure, coronary insufficiency)
- Hemoptysis
- Diaphoresis
- Spinal cord injury above T8
- Use of any type of home MV support prior to hospitalization
- Skeletal pathology that impairs chest wall movements
- Poor general prognosis or fatal outcome
The study team makes the final eligibility decision.
Where it's taking place
- Leuven, Belgium
Compensation & support
A stipend or compensation may be offered.
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Leuven, Belgium. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.