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New treatment option for Multiple Sclerosis
Official title Voluntary Activation During Isokinetic Contractions in Subjects with Neuromotor Disorders
ClinicalTrials.gov ID: NCT04607174
What this study is testing
- What it's testing
- Activation is the amount of voluntary recruitment of a muscle during voluntary contraction. Full activation implies the recruitment of all muscle fibres at their tetanic frequency.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 70
You may be able to join if
- age between 18 and 70 years old;
- ability to sign the informed consent form;
- ability to understand the instructions and to complete the motor task;
- voluntary knee flexion-extension range of at least 70°;
- maximal extension of angle \< 30° (0°=full extension, 180° sagittal tibio-femural angle).
You likely can't join if
- pregnancy;
- a history of epilepsy (to avoid the risk for seizures triggered by the stimuli);
- Mini Mental State Examination ≤27/30;
- implanted electro-sensitive devices;
- any orthopedic condition limiting the articular mobility or muscular strength of the lower limbs;
- current treatment with oral anticoagulant therapy (to avoid the risk for muscle hemorrhage);
See the full eligibility criteria
- age between 18 and 70 years old;
- ability to sign the informed consent form;
- ability to understand the instructions and to complete the motor task;
- voluntary knee flexion-extension range of at least 70°;
- maximal extension of angle \< 30° (0°=full extension, 180° sagittal tibio-femural angle).
- pregnancy;
- a history of epilepsy (to avoid the risk for seizures triggered by the stimuli);
- Mini Mental State Examination ≤27/30;
- implanted electro-sensitive devices;
- any orthopedic condition limiting the articular mobility or muscular strength of the lower limbs;
- current treatment with oral anticoagulant therapy (to avoid the risk for muscle hemorrhage);
- medium/serius osteoporosis (femoral Bone Mineral Density on the affected side, t-score \< (-3.5));
- familiarity with the testing method.
The study team makes the final eligibility decision.
Where it's taking place
- Milan, MI, Italy
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 70 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Milan, MI, Italy. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.