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Compares treatment options for Myocardial Infarction
Official title Low Dose Rosuvastatin Plus Ezetimibe Versus High-dose Rosuvastatin in AMI
ClinicalTrials.gov ID: NCT04499859
What this study is testing
What is Ezetimibe 10mg + Rosuvastatin 5mg?
Ezetimibe 10mg + Rosuvastatin 5mg is an investigational medicine, being studied as a potential treatment for myocardial infarction.
Also referred to as Rosuzet 10/5 mg.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Combination therapy of rosuvastatin 5mg and ezetimibe 10 mg showed similar achievement rate in decreasing LDL cholesterol level by 50% as single use of rosuvastatin 20 mg. This trial aims to prove non-inferiority of concomitant usage of low dose rosuvastatin and ezetimibe among patients with acute myocardial infarction who went through percutaneous coronary intervention at decreasing major adverse cardiac events compared to the efficacy of single use of high dose rosuvastatin.
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 19 and older
You may be able to join if
- Adults Aged 19 and up
- Patients diagnosed with myocardial infarction (both ST segment elevation and non-ST segment elevation) who were treated with percutaneous coronary...
- For female patients who are of childbearing age, people that agreed on taking mandatory pregnancy test
- Patients who agreed and signed on the informed consent form
You likely can't join if
- Patients with life expectancy of a year or less due to malignancy
- Patients with chronic liver disease
- Patients with sensitivity to active ingredient of the research drugs (ezetimibe and/or rosuvastatin) or patients who are prohibited to take ezetimibe...
- Pregnant and/or breastfeeding
- Female patients who are unable to use any means of contraception
- Patients receiving hemodialysis, peritoneal dialysis patients and/or kidney transplant patients, due to end stage renal disease
See the full eligibility criteria
- Adults Aged 19 and up
- Patients diagnosed with myocardial infarction (both ST segment elevation and non-ST segment elevation) who were treated with percutaneous coronary intervention (Myocardial infarction defined as in the 4th Universal...
- For female patients who are of childbearing age, people that agreed on taking mandatory pregnancy test
- Patients who agreed and signed on the informed consent form
- Patients with life expectancy of a year or less due to malignancy
- Patients with chronic liver disease
- Patients with sensitivity to active ingredient of the research drugs (ezetimibe and/or rosuvastatin) or patients who are prohibited to take ezetimibe and/or rosuvastatin.
- Pregnant and/or breastfeeding
- Female patients who are unable to use any means of contraception
- Patients receiving hemodialysis, peritoneal dialysis patients and/or kidney transplant patients, due to end stage renal disease
- Patients who participated in other clinical trial(s) within 3 months from the screening (except non-treatment observational study)
- Patients considered inappropriate for the study for any other reason(s) by the inspector(s)
The study team makes the final eligibility decision.
Where it's taking place
- Bucheon-si, Gyeonggido, South Korea
- Suwon, Gyeonggido, South Korea
- Uijeongbu-si, Gyeonggido, South Korea
- Daejeon, South Korea
- Incheon, South Korea
- Seoul, South Korea
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 19 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Bucheon-si, Gyeonggido, South Korea; Suwon, Gyeonggido, South Korea; Uijeongbu-si, Gyeonggido, South Korea; Daejeon, South Korea; Incheon, South Korea; Seoul, South Korea. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.