BridgeMD
Compares treatment options for Solid Tumor
Official title Propofol vs Sevo for Paediatric Tumor Surgery
ClinicalTrials.gov ID: NCT04475705
What this study is testing
What is propofol?
propofol is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for solid tumor.
Also referred to as Diprivan.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Background: Retrospective studies and meta-analyses have shown a reduction in 5-year survival following inhalational based compared to propofol based total intravenous (TIVA) anaesthesia for cancer surgery. To date there have been no prospective trials published which evaluate the effect of anaesthetic technique on circulating tumour cells (CTC), oxidative stress, and recurrence rate following cancer surgery.
- Phase 4: studies an already-approved treatment
- Time commitment: about 5 years
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 6 to 18
You may be able to join if
- patients coming for elective primary solid tumor resection for curative intent in Hong Kong Children's Hospital
- AND patients \> 5kg
- AND patients within age limit
You likely can't join if
- Autoimmune / Chronic inflammatory diseases e.g. Systemic Lupus Erythematosus (SLE), Rheumatoid Arthritis (RA) etc.
- Current Steroid therapy
- Surgery for tumour removal in the past year
- Allergy to Propofol
- intraoperative use of nitrous oxide
- Patient susceptible to Malignant Hyperthermia
See the full eligibility criteria
- patients coming for elective primary solid tumor resection for curative intent in Hong Kong Children's Hospital
- AND patients \> 5kg
- AND patients within age limit
- Autoimmune / Chronic inflammatory diseases e.g. Systemic Lupus Erythematosus (SLE), Rheumatoid Arthritis (RA) etc.
- Current Steroid therapy
- Surgery for tumour removal in the past year
- Allergy to Propofol
- intraoperative use of nitrous oxide
- Patient susceptible to Malignant Hyperthermia
- Patients / parents / legal guardians showing preference in anaesthetic techniques during recruitment process
The study team makes the final eligibility decision.
Where it's taking place
- Hong Kong, Hong Kong
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 5 years per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 6 months to 18 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hong Kong, Hong Kong. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.