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Compares treatment options for Knee Osteoarthritis
Official title Fluoroscopic Versus Ultrasound Guidance for Cooled Radiofrequency Ablation of Geniculate Nerves in Knee Osteoarthritis: A Randomized Control Trial
ClinicalTrials.gov ID: NCT04472702
What this study is testing
- What it's testing
- Cooled radiofrequency ablation (cRFA) of the knee geniculate nerves is a promising treatment option for knee osteoarthritis, but has variable efficacy. Fluoroscopy is the typical guidance of choice, but uses bony landmarks to target these nerves which have variable positions around the knee.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 35 to 99
You may be able to join if
- 1) patients of either gender with primary knee OA of one or both knees fulfilling the diagnostic criteria for knee OA by the American College of...
- 2) Kellgren-Lawrence score of two to four,
- 3) reported NPRS pain intensity of at least four on most or all days of the past week
- 4) pain resistant to conventional treatments which may include but is not limited to medications (e.g. acetaminophen, oral or topical non-steroidal...
You likely can't join if
- 1) age \<35 years,
- 2) non-English speaking patients,
- 3) body mass index greater than 40,
- 4) previous radiofrequency ablation procedure for the knee,
- 5) active systemic or local infections at the site of needle/cRFA probe placement,
- 6) previous knee joint replacement surgery,
See the full eligibility criteria
- 1) patients of either gender with primary knee OA of one or both knees fulfilling the diagnostic criteria for knee OA by the American College of Rheumatology,
- 2) Kellgren-Lawrence score of two to four,
- 3) reported NPRS pain intensity of at least four on most or all days of the past week
- 4) pain resistant to conventional treatments which may include but is not limited to medications (e.g. acetaminophen, oral or topical non-steroidal anti-inflammatory drugs, opioids), physical therapy, and...
- 1) age \<35 years,
- 2) non-English speaking patients,
- 3) body mass index greater than 40,
- 4) previous radiofrequency ablation procedure for the knee,
- 5) active systemic or local infections at the site of needle/cRFA probe placement,
- 6) previous knee joint replacement surgery,
- 7) autoimmune or inflammatory cause of knee arthritis such as rheumatoid or psoriatic arthritis,
- 8) non-ambulatory patients,
- 9) patients who are unable to provide their own consent (e.g. dementia),
- 10) unstable medical or psychiatric illness,
- 11) patients with pacemakers, spinal cord stimulators, deep brain stimulators, or similar devices,
- 12) patients seeking care as a part of workman's compensation or have litigation pending
- 13) a negative response to diagnostic geniculate nerve lidocaine injections.
The study team makes the final eligibility decision.
Where it's taking place
- Sacramento, California, United States
- Rochester, New York, United States
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 35 years to 99 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Sacramento, California, United States; Rochester, New York, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.