BridgeMD
New treatment option for Toxoplasmosis, Cerebral
Official title Dexamethasone for Cerebral Toxoplasmosis
ClinicalTrials.gov ID: NCT04341155
What this study is testing
What is Dexamethasone?
Dexamethasone is an investigational medicine, given as an once-daily, being studied as a potential treatment for toxoplasmosis, cerebral.
Also referred to as Dexamethasone - Phapros.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Toxoplasma gondii infects over one third of the global human population. Cerebral toxoplasmosis is the most common opportunistic infection in HIV patients resulting in up to 50% of mortality with proper treatment and 80% without it.
- Phase 2: a mid-size study of how well it works
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age 18 years or above.
- Clinical signs and symptoms compatible to cerebral toxoplasmosis
- Serology HIV positive
- Immunoglobulin G anti-toxoplasma titre is positive
- One or more mass lesions on the neuroradiological finding
You likely can't join if
- History of anti-toxoplasmosis administrattion for more than 5 days before recruitment
- Hypersensitivity or other contraindication to dexamethasone
- Pregnancy
See the full eligibility criteria
- Age 18 years or above.
- Clinical signs and symptoms compatible to cerebral toxoplasmosis
- Serology HIV positive
- Immunoglobulin G anti-toxoplasma titre is positive
- One or more mass lesions on the neuroradiological finding
- None or less than 3 days of dexamethasone therapy taken
- Written informed consent from the patients or from close relatives of the patient if the patient is unconscious.
- History of anti-toxoplasmosis administrattion for more than 5 days before recruitment
- Hypersensitivity or other contraindication to dexamethasone
- Pregnancy
The study team makes the final eligibility decision.
Where it's taking place
- Bandung, West Java, Indonesia
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Bandung, West Java, Indonesia. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.