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New treatment option for Cannabis
Official title Age Differences in the Effects of Cannabis on Simulated Driving
ClinicalTrials.gov ID: NCT04325958
What this study is testing
What is Cannabis?
Cannabis is an investigational medicine, being studied as a potential treatment for cannabis.
Also referred to as Marijuana.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Epidemiological studies suggest that the use of cannabis is associated with an increase in the risk of motor vehicle collisions. It is also known that younger users may be at increased risk for motor vehicle collisions.
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 19 to 45. Healthy volunteers may be eligible.
You may be able to join if
- 19-25 or 35-45 years of age;
- Use of smoked cannabis at least once in the past 6 months.
- Use of smoked or vaped cannabis primarily for recreational purposes on up to 1 day per week or on at least 6 days per week in the past 3 months;
- Holds a class G or G2 Ontario driver's licence (or equivalent from another jurisdiction) for at least 12 months;
- Willing to abstain from using alcohol for 24 hours and cannabis for 72 hours prior to Practice and Test Sessions;
You likely can't join if
- Use of cannabis primarily for therapeutic purposes, or equally for therapeutic and recreational purposes;
- Diagnosis of medical condition that contraindicates use of cannabis determined by self-report as judged by the Principal Investigator and a study...
- Diagnosis of psychiatric condition that contraindicates use of cannabis determined by self-report or SCID-5;
- Participants of childbearing potential: Pregnancy (point-of-care test) or breastfeeding;
- Meets criteria for current or lifetime alcohol or other substance use disorder (DSM-5), except tobacco use disorder and caffeine use disorder;
- Is a regular user of medications that affect brain function (based on self-report); this includes concomitant therapy with sedative-hypnotics or...
See the full eligibility criteria
- 19-25 or 35-45 years of age;
- Use of smoked cannabis at least once in the past 6 months.
- Use of smoked or vaped cannabis primarily for recreational purposes on up to 1 day per week or on at least 6 days per week in the past 3 months;
- Holds a class G or G2 Ontario driver's licence (or equivalent from another jurisdiction) for at least 12 months;
- Willing to abstain from using alcohol for 24 hours and cannabis for 72 hours prior to Practice and Test Sessions;
- Willing to abstain from all other drugs not prescribed for medical purposes for 48 hours prior to Practice and Test Sessions;
- Resides within Toronto (study site) or can reside with friends/family in Toronto after a Test Session; this area may be extended to the Greater Toronto area if recruitment challenges arise;
- Participant willing to use appropriate contraception until their participation in the study is completed;
- Provides written and informed consent.
- Use of cannabis primarily for therapeutic purposes, or equally for therapeutic and recreational purposes;
- Diagnosis of medical condition that contraindicates use of cannabis determined by self-report as judged by the Principal Investigator and a study physician; this includes a history of hypersensitivity to cannabinoids...
- Diagnosis of psychiatric condition that contraindicates use of cannabis determined by self-report or SCID-5;
- Participants of childbearing potential: Pregnancy (point-of-care test) or breastfeeding;
- Meets criteria for current or lifetime alcohol or other substance use disorder (DSM-5), except tobacco use disorder and caffeine use disorder;
- Is a regular user of medications that affect brain function (based on self-report); this includes concomitant therapy with sedative-hypnotics or other psychoactive drugs
- Use of anti-hypertensives;
- First-degree relative diagnosed with schizophrenia or another psychotic disorder.
- Participation in a past driving study at CAMH (to limit practice effects).
- Participation in a clinical study concurrent with their participation in this study.
The study team makes the final eligibility decision.
Where it's taking place
- Toronto, Ontario, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 19 years to 45 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Toronto, Ontario, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.