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New treatment option for Schizophrenia
Official title Effects of Brain Stimulation on Cognition, Oscillations and GABA Levels in Schizophrenia
ClinicalTrials.gov ID: NCT04267003
What this study is testing
- What it's testing
- People with schizophrenia often have problems with attention, learning and memory and other cognitive abilities that interfere with their work and school performance. Unfortunately, even our best treatments often do not significantly reduce these cognitive problems.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 47. Healthy volunteers may be eligible.
You may be able to join if
- Participants must be able to sufficiently speak and understand English so as to be able to understand and complete cognitive tasks.
- All people must have the ability to give valid informed consent. for Patients with Schizophrenia Only:
- Diagnosis of schizophrenia, schizophreniform or schizoaffective disorder
- No medication changes in the prior month
- No medication changes anticipated in the upcoming month
You likely can't join if
- Pacemakers
- Implanted electrical (brain and spinal) stimulators
- Implanted defibrillator
- Metallic implants
- Skin damage or skin conditions such as eczema at the sites where electrodes will be placed
- Hair styles hindering the placement of electrodes
See the full eligibility criteria
- Participants must be able to sufficiently speak and understand English so as to be able to understand and complete cognitive tasks.
- All people must have the ability to give valid informed consent. for Patients with Schizophrenia Only:
- Diagnosis of schizophrenia, schizophreniform or schizoaffective disorder
- No medication changes in the prior month
- No medication changes anticipated in the upcoming month
- Stable outpatient or partial hospital status
- Normal IQ (\>70; IQ will be measured by administering the Wechsler Abbreviated Scale of
- Intelligence (WASI) test)
- Must not be currently taking the antipsychotic clozapine
- Pacemakers
- Implanted electrical (brain and spinal) stimulators
- Implanted defibrillator
- Metallic implants
- Skin damage or skin conditions such as eczema at the sites where electrodes will be placed
- Hair styles hindering the placement of electrodes
- Cranial pathologies
- Head trauma
- Epilepsy
- Mental retardation
- Any known history of neurological disorders (including epilepsy, amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), stroke, cerebral palsy, any DSM-5 axis I psychiatric disorder (for healthy control people)...
- Uncorrected vision problems that would hinder cognitive testing (this also pertains to people with color blindness in tasks where discriminating colored objects/items is necessary for successful performance)
- Pregnancy
- Substance dependence in the past six months
- Substance abuse in the past month
The study team makes the final eligibility decision.
Where it's taking place
- Sacramento, California, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 47 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Sacramento, California, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.