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New treatment option for Acute Respiratory Distress Syndrome
Official title Early Use of Airway Pressure Release Ventilation (APRV) in ARDS
ClinicalTrials.gov ID: NCT04221737
What this study is testing
- What it's testing
- Airway pressure release ventilation (APRV) is a time-cycled, pressure controlled, intermittent mandatory ventilation mode with extreme inverse I:E ratios. Currently it is considered as a non-conventional ventilatory mode.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- Acute respiratory distress syndrome, according to the Berlin definition of ARDS, with adjusted pO2/FiO2 for altitude \<300, and less than 48 h of...
You likely can't join if
- Pregnancy
- Less than 18 years-old
- Expected duration of mechanical ventilation less than 48 h
- Preexisting conditions with an expected 3-month mortality exceeding 50%
- Concurrent chemotherapy
- Confirmed intracranial hypertension
See the full eligibility criteria
- Acute respiratory distress syndrome, according to the Berlin definition of ARDS, with adjusted pO2/FiO2 for altitude \<300, and less than 48 h of endotracheal mechanical ventilation
- Pregnancy
- Less than 18 years-old
- Expected duration of mechanical ventilation less than 48 h
- Preexisting conditions with an expected 3-month mortality exceeding 50%
- Concurrent chemotherapy
- Confirmed intracranial hypertension
- Catastrophic cranial trauma or neuromuscular disorders that are known to prolong mechanical ventilation
- Pneumothorax at enrollment (resolved or not)
- Do-not-resuscitate order
The study team makes the final eligibility decision.
Where it's taking place
- Guadalajara, Jalisco, Mexico
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Guadalajara, Jalisco, Mexico. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.