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New treatment option for Diabetes
Official title Evaluating Glial Acetate Metabolism as a Biomarker of Hypoglycemic Counterregulation
ClinicalTrials.gov ID: NCT04207619
What this study is testing
- What it's testing
- Hypoglycemic complications are a major impediment to the maintenance of healthy glucose levels in persons with diabetes. The investigators recently completed a clinical pilot and feasibility study (GLIMPSE, NCT02690168), which identified a novel biomarker, glial acetate metabolism, that appears to predict the susceptibility to hypoglycemia.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 40. Healthy volunteers may be eligible.
You may be able to join if
- Healthy male or female
- Ages 18-40 years
- BMI between 20 kg/m2 and 30 kg/m2 (±0.5 kg/m2 will be accepted)
- Medically cleared for participation in the study
You likely can't join if
- Contraindication to MRI
- Consume \>10 alcoholic drinks/week
- History of chronic smoking or have quit less than 10 years ago
- History of clinically diagnosed diabetes or a fasting blood glucose \>126 mg/dL
- Average screening blood pressure \>140/90 mmHg
- History of cardiovascular disease
See the full eligibility criteria
- Healthy male or female
- Ages 18-40 years
- BMI between 20 kg/m2 and 30 kg/m2 (±0.5 kg/m2 will be accepted)
- Medically cleared for participation in the study
- Contraindication to MRI
- Consume \>10 alcoholic drinks/week
- History of chronic smoking or have quit less than 10 years ago
- History of clinically diagnosed diabetes or a fasting blood glucose \>126 mg/dL
- Average screening blood pressure \>140/90 mmHg
- History of cardiovascular disease
- Pregnant, planning to become pregnant, or breastfeeding
- Use of medications affecting glucose metabolism, e.g., benzodiazepines, thiazide diuretics, cortisone, and prednisone.
- Use of beta-adrenergic antagonists.
- Based on the investigative team's clinical judgement, a subject may not be appropriate for participation in the study.
The study team makes the final eligibility decision.
Where it's taking place
- Baton Rouge, Louisiana, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 40 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Baton Rouge, Louisiana, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.