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New treatment option for Trauma
Official title Magnesium Infusion for Pain Management in Critically Ill Trauma Patients
ClinicalTrials.gov ID: NCT04166877
What this study is testing
What is Magnesium Sulfate in Parenteral Dosage Form?
Magnesium Sulfate in Parenteral Dosage Form is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for trauma.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Magnesium is a naturally occurring mineral that is important for your body and brain. Magnesium sulfate (study drug) is a medication containing magnesium that is commonly used to improve low blood levels of magnesium.
- Phase 4: studies an already-approved treatment
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- All trauma patients admitted to an adult intensive care unit
- Signed informed consent
- Hospital or trauma multimodal pain management order set used for pain management
- Ages 18-99
You likely can't join if
- Admission to the Pediatric Intensive Care Unit.
- Head Abbreviated Injury Score (AIS) of greater than 1
- Known heart failure with reduced ejection fraction (EF \< 40%)
- Renal failure (GFR \< 60)
- Cardiac arrhythmia (except for sinus tachycardia)
- Greater than 5% TBSA burn injuries
See the full eligibility criteria
- All trauma patients admitted to an adult intensive care unit
- Signed informed consent
- Hospital or trauma multimodal pain management order set used for pain management
- Ages 18-99
- Admission to the Pediatric Intensive Care Unit.
- Head Abbreviated Injury Score (AIS) of greater than 1
- Known heart failure with reduced ejection fraction (EF \< 40%)
- Renal failure (GFR \< 60)
- Cardiac arrhythmia (except for sinus tachycardia)
- Greater than 5% TBSA burn injuries
- Moderate to severe alcohol withdrawal protocol ordered for patient
- Regular use of opioids in the week prior to injury
- Receiving continuous infusion of opioids
- Patients expected to require general anesthesia between 24 and 48 hours after admission (during study drug administration)
- Patients unable to provide consent is unavailable
- Patients unable to provide a pain score
- Pregnancy
- Prisoners
The study team makes the final eligibility decision.
Where it's taking place
- Sacramento, California, United States
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Sacramento, California, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.