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New treatment option for Obsessive-Compulsive Disorder
Official title Brain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCD
ClinicalTrials.gov ID: NCT04131829
What this study is testing
What is Fluoxetine - immediate treatment?
Fluoxetine - immediate treatment is an investigational medicine, being studied as a potential treatment for obsessive-compulsive disorder.
Also referred to as fluoxetine, prozac.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The proposed randomized, double-blind research study will use functional magnetic resonance neuroimaging using state-of-the-art HCP acquisition protocols and analytic pipelines, to identify predictors and correlates of response to an accepted first-line pharmacological treatment for obsessive-compulsive disorder.
- Phase 2: a mid-size study of how well it works
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65. Healthy volunteers may be eligible.
You may be able to join if
- for all groups will include: (i) Adults, Men and women will be included, in a 1:1 ratio; and efforts will be made to recruit racial and ethnic...
- Additional
- OCD Participants: (i) a DSM diagnosis of OCD, established as detailed above; (ii) a baseline Y-BOCS of ≥16; (iii) no current psychoactive medication...
- Healthy Control Participants: (i) no current DSM diagnosis (by clinician interview confirmed by SCID or MINI); (ii) no documented or clinically...
You likely can't join if
- Exclusion criteria for all groups will include: (i) any unstable medical, psychiatric, or neurological condition (including active or otherwise...
- Additional exclusion criteria:
- OCD Participants: (i) past allergy or adverse reaction to fluoxetine or another SSRI, or other clinical contraindication to fluoxetine...
The study team makes the final eligibility decision.
Where it's taking place
- New Haven, Connecticut, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include New Haven, Connecticut, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.