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New treatment option for VHL Pancreatic Neuroendocrine Tumors
Official title Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors
ClinicalTrials.gov ID: NCT04074135
What this study is testing
What is 68-Gallium DOTATATE?
68-Gallium DOTATATE is an investigational medicine, being studied as a potential treatment for vhl pancreatic neuroendocrine tumors.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Background: People with von Hippel-Lindau (VHL) can have problems with a variety of organs, such as the pancreas. The disease can cause tumors of the pancreas.
- Phase 2: a mid-size study of how well it works
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 12 and older
You may be able to join if
- INCLUSION CRITIERIA:
- Participants who have been diagnosed with VHL using the following criteria: \-- Identification of a heterozygous germline pathogenic variant in VHL...
- Participants with at least 1 pancreatic manifestation of VHL as documented on any non-invasive imaging study. These manifestations may include:
- Pancreatic cyst(s)
- Solid lesions suspicious for microcystic adenoma(s)
You likely can't join if
- 1\. Inability of participant to undergo serial non-invasive imaging.
See the full eligibility criteria
- INCLUSION CRITIERIA:
- Participants who have been diagnosed with VHL using the following criteria: \-- Identification of a heterozygous germline pathogenic variant in VHL by molecular genetic testing. or \-- Clinical criteria
- Participants with at least 1 pancreatic manifestation of VHL as documented on any non-invasive imaging study. These manifestations may include:
- Pancreatic cyst(s)
- Solid lesions suspicious for microcystic adenoma(s)
- Solid enhancing lesions suspicious for PNET(s)
- Any other solid lesion(s) of the pancreas
- Age greater than or equal to 12 years.
- Ability of participant to understand and the willingness to sign a written informed consent document.
- 1\. Inability of participant to undergo serial non-invasive imaging.
The study team makes the final eligibility decision.
Where it's taking place
- Bethesda, Maryland, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 12 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Bethesda, Maryland, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.