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New treatment option for Acute Myocardial Infarction
Official title Impact of Treating Severe Periodontitis on Inflammatory Activity of Atheromatous Plaques in Patients With Acute Myocardial Infarction (AMI)
ClinicalTrials.gov ID: NCT04046237
What this study is testing
- What it's testing
- Multicenter randomized clinical trial with two arms in patients hospitalized for an AMI nested in the Frenchie registry. Periodontal therapy is performed by periodontists in the intervention group versus treatment by dental surgeons as part of their usual practice in the control group.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 30 to 70
You may be able to join if
- Patients hospitalized for an acute myocardial infarction and included in the Frenchie registry
- Score ≥ 5 on the screening questionnaire for periodontitis
- Six teeth at least (excluding wisdom teeth)
- Consent signature
- Affiliation to a French medical insurance (Sécurité Sociale)
You likely can't join if
- Patients with diseases,other than cardiovascular and diabetes, known to change the periodontal state such as AIDS, rheumatoid arthritis...
- Systemic antibiotic therapy\> 48 hours in the 3 months prior to inclusion
- Acute heart failure
- Uncontrolled ventricular rhythm disorders
- Impossibility for the patient to attend follow-up visits
- Impossibility to maintain the extended position for 20 minutes
See the full eligibility criteria
- Patients hospitalized for an acute myocardial infarction and included in the Frenchie registry
- Score ≥ 5 on the screening questionnaire for periodontitis
- Six teeth at least (excluding wisdom teeth)
- Consent signature
- Affiliation to a French medical insurance (Sécurité Sociale)
- Patients with diseases,other than cardiovascular and diabetes, known to change the periodontal state such as AIDS, rheumatoid arthritis, Chediak-Higashi syndrome, Papillon-Lefèvre
- Systemic antibiotic therapy\> 48 hours in the 3 months prior to inclusion
- Acute heart failure
- Uncontrolled ventricular rhythm disorders
- Impossibility for the patient to attend follow-up visits
- Impossibility to maintain the extended position for 20 minutes
- Immunosuppressive therapy\> 1 month in the 6 months prior to inclusion
- Pregnancy, breastfeeding
- Known hypersensitivity to chlorhexidine, povidone, 18-fluoro-deoxyglucose
The study team makes the final eligibility decision.
Where it's taking place
- Paris, France
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 30 years to 70 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Paris, France. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.