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New treatment option for Lipodystrophy
Official title Low Energy Diet and Familial Partial Lipodystrophy
ClinicalTrials.gov ID: NCT03900286
What this study is testing
- What it's testing
- To evaluate the therapeutic efficacy and metabolic impact of a low energy diet (LED) in people with familial partial lipodystrophy and diabetes. Participants will be provided with a LED (total diet replacement) for 12 weeks, before the introduction of a stepped food transition.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 99
You may be able to join if
- Familial Partial Lipodystrophy
- Age \>= 18 yrs
- T2DM
- Willingness to check daily blood sugars
- HbA1c between 53mmol(7%)- 108 mmol(12%)
You likely can't join if
- Pregnancy
- Untreated thyroid dysfunction (patients who have been euthyroid on medication for at least 3 months can be included)
- Use of medication adversely that affects diabetes control (e.g. steroids/ immunosuppressants/ certain antipsychotics)
- Incapacity to give informed consent
- History of an eating disorder/ purging behaviour
- Previous gastric bypass/ banding
See the full eligibility criteria
- Familial Partial Lipodystrophy
- Age \>= 18 yrs
- T2DM
- Willingness to check daily blood sugars
- HbA1c between 53mmol(7%)- 108 mmol(12%)
- Weight stable for 3 months
- Capacity to consent
- Pregnancy
- Untreated thyroid dysfunction (patients who have been euthyroid on medication for at least 3 months can be included)
- Use of medication adversely that affects diabetes control (e.g. steroids/ immunosuppressants/ certain antipsychotics)
- Incapacity to give informed consent
- History of an eating disorder/ purging behaviour
- Previous gastric bypass/ banding
- Use of Leptin Therapy
- Untreated retinopathy
The study team makes the final eligibility decision.
Where it's taking place
- Cambridge, United Kingdom
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 99 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Cambridge, United Kingdom. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.