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Official title Neurobiological Mechanisms of Aging and Stress on Prospective Navigation
ClinicalTrials.gov ID: NCT03896529
What this study is testing
- What it's testing
- Two hallmarks of both healthy aging and age-related disease are 1) memory and navigational deficits, particularly in orienting towards goal locations and planning how to navigate to them, and 2) increased susceptibility to stress and altered regulation of the stress response. However, there are marked individual differences in these age-related changes.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 65 to 80. Healthy volunteers may be eligible.
You may be able to join if
- adults 65-80
- U.S. citizens or permanent residents
- who speak fluent English
- willing to come to Georgia Tech to participate in group testing sessions.
You likely can't join if
- Individuals will be carefully screened using IRB-approved procedures for safety contraindications to MRI and electrical shock stimulation
- (e.g., metal or electrical implants, heart arrhythmia, or medication affecting the cardiovascular system [e.g. beta-blockers]). The purpose of this...
- Epilepsy
- Dementia
- Parkinson's disease
- history of stroke or seizure
See the full eligibility criteria
- adults 65-80
- U.S. citizens or permanent residents
- who speak fluent English
- willing to come to Georgia Tech to participate in group testing sessions.
- Individuals will be carefully screened using IRB-approved procedures for safety contraindications to MRI and electrical shock stimulation
- (e.g., metal or electrical implants, heart arrhythmia, or medication affecting the cardiovascular system [e.g. beta-blockers]). The purpose of this study is to investigate mechanisms of normally functioning memory, and...
- Epilepsy
- Dementia
- Parkinson's disease
- history of stroke or seizure
- psychiatric disorders
- untreated depression or emotional conditions
- Attention Deficit Disorder
- Multiple Sclerosis
- uncontrolled hyper- or hypo-tension
- untreated Diabetes
- Sickle Cell Anemia
- regularly use illegal or psychoactive drugs (e.g., cocaine, alcohol abuse, etc).
- Additionally, individuals scoring \< 3 on WAIS-R forward span, \< 2 on WAIS-R backward span, and failing to name more than 2 vegetable names will be excluded from the study. These exclusions will insure that persons...
The study team makes the final eligibility decision.
Where it's taking place
- Atlanta, Georgia, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 65 years to 80 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Atlanta, Georgia, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.