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New treatment option for Metastatic Melanoma
Official title Interim FDG PET-CT in Melanoma Metastatic Patient's Treated by Anti-PD1 Therapy
ClinicalTrials.gov ID: NCT03888950
What this study is testing
- What it's testing
- The objective of this study is to assess whether FDG (18F-2-fluoro-2-deoxy-D-glucose fluorodeoxyglucose) PET-CT could be an early predictive method of therapeutic response to anti-PD-1 immunotherapy in metastatic melanoma after 2 cycles of ANTI-PD1. 20 patients will be enrolled and undergo three PET/CT scans: a baseline PET-CT, an early research PET-CT after 2 cycles of anti-PD1 (PET1) and a PET-CT at 3 months of initiation of treatment.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age greater than or equal to 18 years,
- Patient with advanced melanoma proved histologically, not BRAF mutated, BRAFV600 mutated and wild mutated, cutaneous or unknown primary melanoma...
- Patient having social insurance,
- Patient who has signed informed consent.
You likely can't join if
- Age less than 18 years,
- Patient with ocular or mucosal melanoma,
- Contraindication to PET CT examination: Severe claustrophobia, unbalanced diabetes (fasting hairy blood glucose ≥ 11 mmol),
- Patient with only metastatic lesions less than 8 mm in size, with the exception of pulmonary nodules,
- HIV and/or HCV (hepatitis C virus) and/or HBV (hepatitis B virus) positive serology, active autoimmune disease,
- Withdrawal of informed consent,
See the full eligibility criteria
- Age greater than or equal to 18 years,
- Patient with advanced melanoma proved histologically, not BRAF mutated, BRAFV600 mutated and wild mutated, cutaneous or unknown primary melanoma having an indication of treatment with anti-PD-1 immunotherapy by...
- Patient having social insurance,
- Patient who has signed informed consent.
- Age less than 18 years,
- Patient with ocular or mucosal melanoma,
- Contraindication to PET CT examination: Severe claustrophobia, unbalanced diabetes (fasting hairy blood glucose ≥ 11 mmol),
- Patient with only metastatic lesions less than 8 mm in size, with the exception of pulmonary nodules,
- HIV and/or HCV (hepatitis C virus) and/or HBV (hepatitis B virus) positive serology, active autoimmune disease,
- Withdrawal of informed consent,
- Metastatic disease not confirmed histologically.
The study team makes the final eligibility decision.
Where it's taking place
- Nice, CHU de NICE, France
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Nice, CHU de NICE, France. Enter your location above to see the nearest site and check your eligibility.
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BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.