BridgeMD
New treatment option for Subfertility
Official title Oral Dydrogesterone as Luteal Phase Support in Natural Cycle FET
ClinicalTrials.gov ID: NCT03859921
What this study is testing
What is Dydrogesterone?
Dydrogesterone is an investigational medicine, given as an once-daily pill taken by mouth, being studied as a potential treatment for subfertility.
Also referred to as Duphaston.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This randomised double-blinded controlled trial aims to compare the live birth rate in natural FET cycles with and without oral dydrogesterone as luteal phase support. The hypothesis is that the use of oral dydrogesterone will increase the live birth rate of natural cycle FET.
- Phase 3: a large, late-stage study
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 42, women only
You may be able to join if
- Age of women \<43 years at the time of stimulated IVF
- Replacing early cleavage embryos or blastocysts after thawing
You likely can't join if
- Requiring hormonal replacement cycles
- Use of donor oocytes or embryos
- Undergoing preimplantation genetic testing
- Presence of hydrosalpinx not corrected surgically prior to FET
- Refusal to join the study
The study team makes the final eligibility decision.
Where it's taking place
- Hong Kong, Hong Kong, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18 years to 42 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hong Kong, Hong Kong, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.