BridgeMD
Compares treatment options for Cardiac Arrest, Out-Of-Hospital
Official title Epinephrine Dose: Optimal Versus Standard Evaluation Trial
ClinicalTrials.gov ID: NCT03826524
What this study is testing
What is Epinephrine?
Epinephrine is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for cardiac arrest, out-of-hospital.
Also referred to as Adrenaline.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The objective of this randomized controlled trial is to evaluate the effectiveness of a low cumulative dose of epinephrine compared to a standard cumulative dose of epinephrine during resuscitation from ventricular fibrillation (VF) or ventricular tachycardia (VT) in adult out-of-hospital cardiac arrest (OHCA) patients.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Out-of-hospital cardiac arrest treated by paramedics
- Initial recorded cardiac rhythm of VF or pulseless VT, or, AED shock on first analysis administered or witnessed by EMS (paramedic or fire)
- Established intravenous vascular access
You likely can't join if
- Known or apparent age \<18 years
- Initial recorded cardiac rhythm of VF or pulseless VT, or, AED shock on first analysis administered or confirmed by paramedics
- Cardiac arrest due to an obvious non-cardiac primary cause (e.g. blunt or penetrating trauma, exsanguination, burns, drug overdose, drowning...
- Administration of intramuscular, endotracheal tube, or intraosseous epinephrine
- Prisoners or persons in police custody
- Known allergy or sensitivity to epinephrine
The study team makes the final eligibility decision.
Where it's taking place
- Victoria, British Columbia, Canada
- Brampton, Ontario, Canada
- London, Ontario, Canada
- Oakville, Ontario, Canada
- Ottawa, Ontario, Canada
- Thunder Bay, Ontario, Canada
- Windsor, Ontario, Canada
- Saskatoon, Saskatchewan, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Victoria, British Columbia, Canada; Brampton, Ontario, Canada; London, Ontario, Canada; Oakville, Ontario, Canada; Ottawa, Ontario, Canada; Thunder Bay, Ontario, Canada and 2 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.