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New treatment option for Obstructive Sleep Apnea
Official title Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea
ClinicalTrials.gov ID: NCT03736382
What this study is testing
- What it's testing
- Mild intermittent hypoxia (IH) initiates sustained increases in chest wall and upper airway muscle activity in humans. This sustained increase is a form of respiratory plasticity known as long-term facilitation (LTF).
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 60
You may be able to join if
- Body mass index \< 40 kg/m\^2.
- 18 to 60 years old.
- Newly diagnosed sleep apnea (i.e. apnea/hypopnea index \ 85 %) that has not been treated.
- Diagnosed with prehypertension or Stage 1 hypertension as categorized by the American Heart Association
- Not pregnant.
You likely can't join if
- Any disease other than high blood pressure and sleep apnea.
- Medications for high blood pressure and sleep promoting supplements including melatonin
- Current effective CPAP usage (greater than 4 hours per night).
- Night Shift workers or recently traveled across time zones.
See the full eligibility criteria
- Body mass index \< 40 kg/m\^2.
- 18 to 60 years old.
- Newly diagnosed sleep apnea (i.e. apnea/hypopnea index \ 85 %) that has not been treated.
- Diagnosed with prehypertension or Stage 1 hypertension as categorized by the American Heart Association
- Not pregnant.
- Normal lung function.
- Minimal alcohol consumption (i.e. no more than the equivalent of a glass of wine/day)
- A typical sleep/wake schedule (i.e. participants will not be night shift workers or have recently travelled across time zones).
- For spinal cord injured participants (Aim-2): incomplete spinal cord lesions at C3 or below and above T12 (greater than 36 mos. post-SCI) without joint contractures but with signs of voluntary ankle, knee and hip...
- Any disease other than high blood pressure and sleep apnea.
- Medications for high blood pressure and sleep promoting supplements including melatonin
- Current effective CPAP usage (greater than 4 hours per night).
- Night Shift workers or recently traveled across time zones.
The study team makes the final eligibility decision.
Where it's taking place
- Detroit, Michigan, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 60 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Detroit, Michigan, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.