BridgeMD
New treatment option for Burns
Official title A Pilot Trial of Disposable Nitrous Oxide Canisters in Providing Pain Control During Burn Dressing Changes
ClinicalTrials.gov ID: NCT03695887
What this study is testing
What is Nitrous Oxide Inhalant Product?
Nitrous Oxide Inhalant Product is an investigational medicine, given as an inhaled treatment, being studied as a potential treatment for burns.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Improvements in burn care have resulted in increased survival. Despite these improved outcomes one of the leading challenges of burn care remains providing adequate analgesia during routine wound care and dressing changes.
- Phase 1: an early, usually small safety study
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- adult burn patients admitted to the Health Sciences Centre
- total body surface area burned of 5-20%
You likely can't join if
- admitted to intensive care unit
- unable to participate in the measurement outcomes (sedated, cognitively impaired, unable to understand English or visually impaired)
- medical condition that precludes using nitrous oxide (respiratory disease and significant cardiovascular disease 5).
- pregnant
- physically unable to hold the canister
- \<90% SaO2 on room air
See the full eligibility criteria
- adult burn patients admitted to the Health Sciences Centre
- total body surface area burned of 5-20%
- admitted to intensive care unit
- unable to participate in the measurement outcomes (sedated, cognitively impaired, unable to understand English or visually impaired)
- medical condition that precludes using nitrous oxide (respiratory disease and significant cardiovascular disease 5).
- pregnant
- physically unable to hold the canister
- \<90% SaO2 on room air
- face burn
- pre-injury narcotics (relative exclusion)
- use of IV ketamine
- pre-existing lung injury
The study team makes the final eligibility decision.
Where it's taking place
- Winnipeg, Manitoba, Canada
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Winnipeg, Manitoba, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.