BridgeMD
New treatment option for Pilon Fracture
Official title Pilon Fracture With Intra-articular Injection of N-Acetylcysteine (Pilon NAC)
ClinicalTrials.gov ID: NCT03652753
What this study is testing
What is N-acetylcysteine?
N-acetylcysteine is an investigational medicine, given as an injectable medicine, being studied as a potential treatment for pilon fracture.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- High energy intra-articular fractures of the distal tibia, or Pilon fracture, is a devastating injury with multiple short and long term complications. The incidence of these injuries is increasing as survival rates after motor vehicle collisions increase.
- Phase 4: studies an already-approved treatment
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Closed high energy pilon fracture requiring a staged procedure
You likely can't join if
- Younger than 18
- Open fracture
- Intra-articular injury not requiring a staged procedure
- Allergy to NAC
- Wounds preventing safe intra-articular injection
- Unwilling to participate in the study
See the full eligibility criteria
- Closed high energy pilon fracture requiring a staged procedure
- Younger than 18
- Open fracture
- Intra-articular injury not requiring a staged procedure
- Allergy to NAC
- Wounds preventing safe intra-articular injection
- Unwilling to participate in the study
- Pregnancy
The study team makes the final eligibility decision.
Where it's taking place
- Columbia, Missouri, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Columbia, Missouri, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.