Recruiting PHASE1 Healthy

New treatment option for Healthy

Official title Alternation in the Human Microbiome With Commonly Used Topical Medications

ClinicalTrials.gov ID: NCT03437005

What this study is testing

What is Desonide 0.05%?

Desonide 0.05% is an investigational medicine, given as an once-daily treatment applied to the skin, being studied as a potential treatment for healthy.

Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.

What it's testing
The global aim of this study is to investigate how the human microbiome changes from baseline with commonly used topical medications such as topical antifungals, low to mid potency topical steroids and emollients. The specific aims are as follows: 1.
  • Phase 1: an early, usually small safety study

A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.

Who can take part

Ages 18 and older. Healthy volunteers may be eligible.

You may be able to join if

  • Adults at least 18 years of age.

You likely can't join if

  • Individuals with known chronically active skin diseases, including atopic dermatitis, psoriasis, seborrheic dermatitis, other autoimmune and...
  • Patients with a history of skin cancer, multiple nevi, or other isolated lesions will not be excluded.
  • Individuals who have used topical, intravenous, intramuscular, or oral antibiotics within the last 6 months
  • Individuals with known allergies to any of the study medications.
  • Individuals younger than 18 years of age.
  • Adults unable to consent
See the full eligibility criteria
Who can join
  • Adults at least 18 years of age.
What rules you out
  • Individuals with known chronically active skin diseases, including atopic dermatitis, psoriasis, seborrheic dermatitis, other autoimmune and inflammatory skin conditions.
  • Patients with a history of skin cancer, multiple nevi, or other isolated lesions will not be excluded.
  • Individuals who have used topical, intravenous, intramuscular, or oral antibiotics within the last 6 months
  • Individuals with known allergies to any of the study medications.
  • Individuals younger than 18 years of age.
  • Adults unable to consent
  • Non-English speaking individuals. Given the complexity in the instructions that people will need to follow for proper sample collection, we will not seek to recruit non-English speaking individuals for this pilot study.
  • Prisoners

The study team makes the final eligibility decision.

Where it's taking place

  • Sacramento, California, United States

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 18 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.

Where is this trial taking place?

Study sites include Sacramento, California, United States. Enter your location above to see the nearest site and check your eligibility.

Explore other conditions

BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.