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New treatment option for Pediatric Anesthesia
Official title Effect of Dexmedetomidine on the Minimum Alveolar Concentration of Sevoflurane
ClinicalTrials.gov ID: NCT03384563
What this study is testing
What is Dexmedetomidine?
Dexmedetomidine is an investigational medicine, given as an inhaled treatment, being studied as a potential treatment for pediatric anesthesia.
Also referred to as Precedex.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The purpose of this protocol is to determine the effect of two clinically applicable Dexmedetomidine dosages (0.5mcg/kg and 1mcg/kg) on the minimum alveolar concentration (MAC) of Sevoflurane in children between the age ranges of: 1-6 months; 6-12 months of age and 12 months-36 months years of age.
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 1 to 36. Healthy volunteers may be eligible.
You likely can't join if
- Interstitial lung disease, chest wall disease, or bronchospastic disease with no flare-ups in the past 2 weeks of presentation
- History of difficult intubation or ventilation
- Airway malformation
- Congenital heart disease
- Cardiac arrhythmias
- Central nervous system disease, including developmental delay, cerebral palsy, or seizure disorder
See the full eligibility criteria
- Interstitial lung disease, chest wall disease, or bronchospastic disease with no flare-ups in the past 2 weeks of presentation
- History of difficult intubation or ventilation
- Airway malformation
- Congenital heart disease
- Cardiac arrhythmias
- Central nervous system disease, including developmental delay, cerebral palsy, or seizure disorder
- History of or family history of malignant hyperthermia
- Electrolyte disorders
- Gastrointestinal disease
- Hepatic dysfunction
- Renal dysfunction
- Metabolic disease, such as diabetes
- Obesity, defined as a body mass index greater than the 95% percentile for age
- Preterm infant (less than 37 weeks gestational age) 15. Use of any medications (anticonvulsants, opioids, benzodiazepines, antibiotics, antihistamines drugs that induce hepatic enzymes) that may affect MAC. Inclusion...
The study team makes the final eligibility decision.
Where it's taking place
- Houston, Texas, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 1 month to 36 months. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Houston, Texas, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.