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New treatment option for Acute Kidney Injury
Official title Effects of Variation of Sodium Dialysate in ICU
ClinicalTrials.gov ID: NCT03329313
What this study is testing
What is Lowering sodium concentration dialysate?
Lowering sodium concentration dialysate is an investigational medicine, given as an once-daily, being studied as a potential treatment for acute kidney injury.
Also referred to as Concentration of sodium in dialysate at 140 mmol/l.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Intermittent hemodialysis/diafiltration is a current renal replacement therapy (RRT) institued for ICU patients with AKI. For a better clinical tolerance, iinternational guidelines advise to use cold dialysate, increase duration session, decrease blood and dialysate flows, and increase level of sodium dialysate concentration (≥ 145mmol/l).
- Phase 2: a mid-size study of how well it works
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- Age \> 18 years old
- Acute kidney injury requiring renal replacement therapy
- Dialysis type: on line sustained low efficiency dialy dialysis -filtration
- SOFA score \> 5
- Sodium serum level between 135 and 145mmol/l
You likely can't join if
- Chronic kidney disease stade IV ou V
- Obstrutive acute kidney injury
- Renal tansplantation in the year before ICU admission
- Moribund with risk of death in the 48 hours
- Vulnerable persons or protected persons
- Pregnant or breastfeeding mother
The study team makes the final eligibility decision.
Where it's taking place
- Montpellier, Montpellier, France
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Montpellier, Montpellier, France. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.