Recruiting NA Myeloid Malignancy

New treatment option for Myeloid Malignancy

Official title Pre-myeloid Cancer and Bone Marrow Failure Clinic Study

ClinicalTrials.gov ID: NCT02958462

What this study is testing

What it's testing
This clinical trial tests next generation sequencing (NGS) for the detection of precursor features of pre-myeloid cancers and bone marrow failure syndromes. NGS is a procedure that looks at relevant cancer associated genes and what they do.

A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.

Who can take part

Ages 18 and older

You may be able to join if

  • Patients with idiopathic cytopenias of unclear significance (ICUS)
  • Patients with clonal hematopoiesis of indeterminate significance (clonal hematopoiesis of indeterminate potential [CHIP]), including the recently...
  • Patients with clonal cytopenias of undetermined significance (CCUS)
  • Marrow failure syndromes with myeloid malignancy predisposition - telomere dysfunction, chromosomal breakage disorders
  • Germ line inherited syndromes with risk for malignant transformation - GATA2, CEBPA, ETV-6, RUNX1, JAK2, PF6, etc.

You likely can't join if

  • Patients under 18 years of age
See the full eligibility criteria
Who can join
  • Patients with idiopathic cytopenias of unclear significance (ICUS)
  • Patients with clonal hematopoiesis of indeterminate significance (clonal hematopoiesis of indeterminate potential [CHIP]), including the recently described CHIP syndrome called VEXAS (vacuoles, E1 ubiquitin ligase, X...
  • Patients with clonal cytopenias of undetermined significance (CCUS)
  • Marrow failure syndromes with myeloid malignancy predisposition - telomere dysfunction, chromosomal breakage disorders
  • Germ line inherited syndromes with risk for malignant transformation - GATA2, CEBPA, ETV-6, RUNX1, JAK2, PF6, etc.
  • Low risk MDS (idiopathic dysplasia of unclear significance)
  • Family member of a patient with one of the above conditions
  • Patient at high risk or suspected of developing one of the above conditions
What rules you out
  • Patients under 18 years of age

The study team makes the final eligibility decision.

Where it's taking place

  • Scottsdale, Arizona, United States
  • Jacksonville, Florida, United States
  • Rochester, Minnesota, United States

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.

Where is this trial taking place?

Study sites include Scottsdale, Arizona, United States; Jacksonville, Florida, United States; Rochester, Minnesota, United States. Enter your location above to see the nearest site and check your eligibility.

Explore other conditions

BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.