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New treatment option for Non-obstructive Azoospermia
Official title Intra-Testicular Transplantation of Autologous Stem Cells for Treatment of Non-Obstructive Azoospermia Male Infertility.
ClinicalTrials.gov ID: NCT02641769
What this study is testing
What is Stem Cell Transplantation?
Stem Cell Transplantation is an investigational medicine, given as an injectable medicine, being studied as a potential treatment for non-obstructive azoospermia.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This is an open label, single arm, single center investigation to assess the safety and efficacy of purified adult autologous, bone marrow derived, highly specialized, differentiation specific into spermatogonial lineages, and mesenchymal stem cells injected into the seminiferous tubules and testis, through a 24-month follow-up period. The investigators' selected model of research is based on maximizing the efficiency of the approach by choosing an autologous pattern which preserves the genetic make-up of an individual that is vital in infertility conditions.
- Phase 2: a mid-size study of how well it works
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 21 to 50, men only
You may be able to join if
- Infertile males with confirmed diagnosis of non-obstructive azoospermia (NOA)
You likely can't join if
- Patients with Obstructive Azoospermia (OA)
- Previous surgical history in Testis
- Patients with infectious genital diseases
- Patients with anatomical abnormalities of the genital tract
- Patients with major medical problems as malignancies
- Chromosomal aberration (e.g. Y microdeletion, trisomy….)
The study team makes the final eligibility decision.
Where it's taking place
- Amman, Amman Governorate, Jordan
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling male, 21 years to 50 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Amman, Amman Governorate, Jordan. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.