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New treatment option for Progressive Supranuclear Palsy
Official title A Molecular Anatomic Imaging Analysis of Tau in Progressive Supranuclear Palsy
ClinicalTrials.gov ID: NCT02605785
What this study is testing
What is F-18 AV 1451?
F-18 AV 1451 is an investigational medicine, being studied as a potential treatment for progressive supranuclear palsy.
Also referred to as Tau binding agent.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is designed to learn more about overall tau burden in the brain of patients with Progressive Supranuclear Palsy (PSP).
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 35 and older. Healthy volunteers may be eligible.
You may be able to join if
- Must be over 35 years of age and present with gradual progression of PSP-related symtoms
- Must have an informant or study partner that can provide independent information of functioning.
- Must meet criteria for possible or probable Progressive Supranuclear Palsy. To fulfill criteria for possible PSP, people must have a gradually...
You likely can't join if
- people will be excluded if they meet criteria for another neurodegenerative disease (including corticobasal syndrome, frontotemporal dementia...
- people with concurrent illnesses that could account for their symptoms, such as traumatic brain injury, encephalitis, strokes or developmental...
- Women that are pregnant or post-partum and breast-feeding will be excluded.
- people will be excluded from the study if they have any of the following genetic conditions which can increase the chance of cancer: Cowden disease...
- people will also be excluded if MRI is contraindicated (metal in head, cardiac pace maker, e.t.c.), if there is severe claustrophobia, if there are...
- people will also be excluded if they do not have an informant, or do not consent to research.
The study team makes the final eligibility decision.
Where it's taking place
- Rochester, Minnesota, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 35 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Rochester, Minnesota, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.