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New treatment option for Non-Small-Cell Lung Cancer (NSCLC)
Official title Hippocampal-Sparing Prophylactic Cranial Irradiation in Pathologically Nodal Positive Non-Small-Cell Lung Cancer
ClinicalTrials.gov ID: NCT02448992
What this study is testing
- What it's testing
- Background. During the clinical course of patients with locoregionally advanced non-small-cell lung cancer (LA-NSCLC) who have undergone aggressive treatment, brain metastasis (BM) is a frequent seen pattern of disease relapse, which cannot be ignored.
- Phase 3: a large, late-stage study
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- Clinical diagnosis of NSCLC
- Must be adult patients (≥ 18 years old) who have received definitive surgery and have a permanent pathology of nodal metastasis
- Platinum-based chemotherapy is mandatory
- Good performance status better than Eastern Cooperative Group (ECOG) of 2 or a general status of Karnofsky (KPS) \> 70 %
- Should have sufficient proficiency in Mandarin language
You likely can't join if
- Have received prior cranial irradiation
- Presence of other active primary cancer (exception of basal cell carcinoma of skin and cervical carcinoma in situ)
- Radiographic evidence of brain metastasis/metastases
- Clinical evidence of extracranial metastatic disease
- Hypersensitivity to magnetic resonance (MR) contrast enhancer
- Serious medical or psychiatric illness
The study team makes the final eligibility decision.
Where it's taking place
- Taoyuan, Taiwan
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Taoyuan, Taiwan. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.