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New treatment option for Colorectal Neoplasms
Official title Screening for Synchronous Metastases in Colorectal Cancer With DW-MRI (SERENADE)
ClinicalTrials.gov ID: NCT02246634
What this study is testing
- What it's testing
- Eligible patients with high risk colorectal malignancy (T3/4, spread greater than 5mm, EMVI positive) will have additional surveillance of breath hold T1, T2 and DW-MRIs (no IV contrast) post surgery six monthly for three years. Findings of liver MRIs as reported by radiology PI will be shared with their local MDT who make decisions as appropriate, including the management of any identified liver metastases, according to local protocol.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 16 and older
You may be able to join if
- Have a high risk primary colorectal malignancy
- Have a negative CT or includes no confirmatory evidence of liver metastases
- Is able to undergo treatment if liver metastasis is found
- Have provided written informed consent to participate in the study
- Be aged 16 years or over
You likely can't join if
- Have had a previous colorectal malignancy
- Have metastatic disease
- Have a synchronous second malignancy
- Are contraindicated for MRI
- Has a T3b or below low rectal tumour without EMVI or N1c
The study team makes the final eligibility decision.
Where it's taking place
- Macclesfield, Cheshire, United Kingdom
- Burton-on-Trent, Derbyshire, United Kingdom
- Chelmsford, Essex, United Kingdom
- Bolton, Greater Manchester, United Kingdom
- Gillingham, Kent, United Kingdom
- Wythenshawe, Manchester, United Kingdom
- Liverpool, Merseyside, United Kingdom
- Stoke-on-Trent, Staffordshire, United Kingdom
- Sutton, Surrey, United Kingdom
- Newport, Wales, United Kingdom
- Nuneaton, Warwickshire, United Kingdom
- Salisbury, Wiltshire, United Kingdom
- Portsmouth, United Kingdom
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 16 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Macclesfield, Cheshire, United Kingdom; Burton-on-Trent, Derbyshire, United Kingdom; Chelmsford, Essex, United Kingdom; Bolton, Greater Manchester, United Kingdom; Gillingham, Kent, United Kingdom; Wythenshawe, Manchester, United Kingdom and 7 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.