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New treatment option for Allogeneic Stem Cell Transplant
Official title Donor-Derived Viral Specific T-cells (VSTs)
ClinicalTrials.gov ID: NCT02048332
What this study is testing
What is Viral specific VST Infusion?
Viral specific VST Infusion is an investigational medicine, given as an once-weekly infusion into a vein, being studied as a potential treatment for allogeneic stem cell transplant.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- In this research study, the investigators want to learn more about the use of donor-derived viral specific T-cells (VSTs) to treat viral infections that occur after allogeneic stem cell transplant. A viral specific T cell is a T lymphocyte (a type of white blood cell) that kills cells that are infected (particularly with viruses).
- Phase 2: a mid-size study of how well it works
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 4 and older
You may be able to join if
- Recipient must be at least 21 days after stem cell infusion
- Clinical status must allow tapering of steroids to 0.5mg/kg prednisone or other steroid equivalent
- Recipient must have achieved engraftment with ANC ≥ 500
You likely can't join if
- Active acute GVHD grades II-IV
- Uncontrolled bacterial or fungal infection
- Uncontrolled relapse of malignancy requiring treatment with chemotherapy
- Infusion of ATG or alemtuzumab within 2 weeks of VST infusion
The study team makes the final eligibility decision.
Where it's taking place
- Akron, Ohio, United States
- Cincinnati, Ohio, United States
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 4 weeks and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Akron, Ohio, United States; Cincinnati, Ohio, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.