Recruiting PHASE4 PPA

New treatment option for PPA

Official title Longitudinal Multi-Modality Imaging in Progressive Apraxia of Speech

ClinicalTrials.gov ID: NCT01818661

What this study is testing

What is AV-1451?

AV-1451 is an investigational medicine, being studied as a potential treatment for ppa.

Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.

What it's testing
The study is designed to determine the relationship between structural and functional changes in the brain on imaging and progression of speech and language, neurological and neuropsychological features in patients with neurodegenerative apraxia of speech (AOS).
  • Phase 4: studies an already-approved treatment

A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.

Who can take part

Ages 18 and older

You may be able to join if

  • We will study people that fulfill clinical for neurodegenerative AOS that have been seen and diagnosed at Mayo Clinic

You likely can't join if

  • people with concurrent illnesses that could account for speech and language deficits, such as traumatic brain injury, strokes or developmental...
  • Women that are pregnant or post-partum and breast-feeding will be excluded. All women who can become pregnant must have a pregnancy test no more than...
  • people will also be excluded if MRI is contraindicated (metal in head, cardiac pace maker, e.t.c.), if there is severe claustrophobia, if there are...
  • people will also be excluded if they do not have an informant, or do not consent to research.

The study team makes the final eligibility decision.

Where it's taking place

  • Rochester, Minnesota, United States

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.

Where is this trial taking place?

Study sites include Rochester, Minnesota, United States. Enter your location above to see the nearest site and check your eligibility.

Explore other conditions

BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.