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New treatment option for Gene Mutation-Related Cancer
Official title COsegregation of VARiants in Panel of Genes
ClinicalTrials.gov ID: NCT01689584
What this study is testing
What is salivary kit?
salivary kit is an investigational medicine, being studied as a potential treatment for gene mutation-related cancer.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The aim of the COVAR project is to achieve reliable classification of as many variants of interest as possible from the French OncoGenetics Database (FrOG, https://frog-db.fr/) in order to use them for the genetic counseling. The results obtained through this study will have a major impact on clinical management of the patients and their families conducting in some cases to propose a prophylactic surgery.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Index cases:
- A person carrying a variant of interest in a gene analyzed in a diagnostic setting by one of the laboratories within the Genetics and Cancer Group...
- Age ≥ 18 years.
- Signed written inform consent "index case" Related parties:
- Any relative of an index case with cancer
You likely can't join if
- Minors
- Persons deprived of liberty or under guardianship (including curators).
- Absence of signed written inform consent
See the full eligibility criteria
- Index cases:
- A person carrying a variant of interest in a gene analyzed in a diagnostic setting by one of the laboratories within the Genetics and Cancer Group (GGC)-Unicancer network, classified as class 3, 4 or hypomorphic class...
- Age ≥ 18 years.
- Signed written inform consent "index case" Related parties:
- Any relative of an index case with cancer
- Any relative without cancer related to an index case, selected by the investigators, according to family structure and degree of related compared to the index case
- For class 4 and hypomorphic class 5 variants; relatives currently undergoing analysis or having already obtained a test result for the variant of interest as part of clinical care.
- Age ≥ 18 years
- Information and signature of the informed consent "selected relatives"
- Minors
- Persons deprived of liberty or under guardianship (including curators).
- Absence of signed written inform consent
The study team makes the final eligibility decision.
Where it's taking place
- Bastia, Corsica, France
- Saint-Cloud, Haut de Seine, France
- Amiens, France
- Angers, France
- Angoulême, France
- Avignon, France
- Besançon, France
- Bordeaux, France
- Bourges, France
- Brest, France
- Caen, France
- Chambéry, France
- Clermont-Ferrand, France
- Colmar, France
- Dijon, France
- Grenoble, France
- La Roche-sur-Yon, France
- La Rochelle, France
- Le Havre, France
- Lille, France
+ 29 more site(s).
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Bastia, Corsica, France; Saint-Cloud, Haut de Seine, France; Amiens, France; Angers, France; Angoulême, France; Avignon, France and 43 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.