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New treatment option for Post-traumatic Stress Disorder
Official title Sympathetic Overactivity in Post-traumatic Stress Disorder
ClinicalTrials.gov ID: NCT01627301
What this study is testing
- What it's testing
- Post-traumatic stress disorder (PTSD) is a highly prevalent anxiety disorder that is associated with an increased risk of cardiovascular (CV) disease and hypertension. One potential mechanism is overactivation of the sympathetic nervous system (SNS), both at rest and particularly during stress.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65. Healthy volunteers may be eligible.
You may be able to join if
- prehypertensive and normotensive veterans with PTSD, and prehypertensive and normotensive veterans without PTSD (controls)
You likely can't join if
- heart or vascular disease
- illicit drug use within the last 6 months
- excessive alcohol use (\>2 drinks per day)
- pregnancy
- autonomic dysfunction
- medications known to affect SNS (clonidine)
See the full eligibility criteria
- prehypertensive and normotensive veterans with PTSD, and prehypertensive and normotensive veterans without PTSD (controls)
- heart or vascular disease
- illicit drug use within the last 6 months
- excessive alcohol use (\>2 drinks per day)
- pregnancy
- autonomic dysfunction
- medications known to affect SNS (clonidine)
- treatment with monoamine oxidase (MAO) inhibitors within the last 14 days
- any serious systemic disease
The study team makes the final eligibility decision.
Where it's taking place
- Decatur, Georgia, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Decatur, Georgia, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.